Literature DB >> 20544401

Gastrointestinal cancer educational case series: the history and management of complex cases in gi oncology. A 72 year-old man with metastatic gastric cancer.

Elizabeth Smyth1, Ghassan K Abou-Alfa, Maeve Lowery, Ali Shamseddine, Ashwaq Al-Olayan, Mohamed Naghy, Derek Power, Teddy Saliba, David Kelsen, Manish A Shah.   

Abstract

INTRODUCTION: Gastric cancer is the third most common cancer worldwide and the second leading cause of cancer deaths. Appropriate staging and treatment options relate to the stage of disease and performance status of the patient. CASE REPORT: Here we present the case of a 72 year old male, with an initial presentation of apparently locally advanced gastric cancer. On discovery of metastatic disease, the utility of palliative gastrectomy, and first and second line chemotherapy are discussed. DISCUSSION: This case demonstrates the potential value of sequential lines of chemotherapy in good performance status patients with advanced gastric cancer. Further research will be necessary in order to assess the utility of newer targeted agents in this setting.

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Year:  2011        PMID: 20544401     DOI: 10.1007/s12029-010-9170-z

Source DB:  PubMed          Journal:  J Gastrointest Cancer


  15 in total

1.  Risk of gastric cancer in hereditary nonpolyposis colorectal cancer in Korea.

Authors:  Y J Park; K H Shin; J G Park
Journal:  Clin Cancer Res       Date:  2000-08       Impact factor: 12.531

Review 2.  Imaging in local staging of gastric cancer: a systematic review.

Authors:  Robert Michael Kwee; Thomas Christian Kwee
Journal:  J Clin Oncol       Date:  2007-05-20       Impact factor: 44.544

Review 3.  Diagnostic approach and management of Lynch syndrome (hereditary nonpolyposis colorectal carcinoma): a guide for clinicians.

Authors:  Yvonne M C Hendriks; Andrea E de Jong; Hans Morreau; Carli M J Tops; Hans F Vasen; Juul Th Wijnen; Martijn H Breuning; Annette H J T Bröcker-Vriends
Journal:  CA Cancer J Clin       Date:  2006 Jul-Aug       Impact factor: 508.702

Review 4.  Chemotherapy in advanced gastric cancer: a systematic review and meta-analysis based on aggregate data.

Authors:  Anna D Wagner; Wilfried Grothe; Johannes Haerting; Gerhard Kleber; Axel Grothey; Wolfgang E Fleig
Journal:  J Clin Oncol       Date:  2006-06-20       Impact factor: 44.544

5.  Expression of glucose transporter-1 in human gastric carcinoma: association with tumor aggressiveness, metastasis, and patient survival.

Authors:  T Kawamura; T Kusakabe; T Sugino; K Watanabe; T Fukuda; A Nashimoto; K Honma; T Suzuki
Journal:  Cancer       Date:  2001-08-01       Impact factor: 6.860

6.  Genotype-phenotype comparison of German MLH1 and MSH2 mutation carriers clinically affected with Lynch syndrome: a report by the German HNPCC Consortium.

Authors:  Timm Goecke; Karsten Schulmann; Christoph Engel; Elke Holinski-Feder; Constanze Pagenstecher; Hans K Schackert; Matthias Kloor; Erdmute Kunstmann; Holger Vogelsang; Gisela Keller; Wolfgang Dietmaier; Elisabeth Mangold; Nicolaus Friedrichs; Peter Propping; Stefan Krüger; Johannes Gebert; Wolff Schmiegel; Josef Rueschoff; Markus Loeffler; Gabriela Moeslein
Journal:  J Clin Oncol       Date:  2006-08-14       Impact factor: 44.544

7.  Associated primary tumors in patients with gastric cancer.

Authors:  Mário Dinis-Ribeiro; Helena Lomba-Viana; Rui Silva; Luís Moreira-Dias; Rafael Lomba-Viana
Journal:  J Clin Gastroenterol       Date:  2002 May-Jun       Impact factor: 3.062

8.  Evaluation of 18F-FDG PET in patients with advanced, metastatic, or recurrent gastric cancer.

Authors:  Takashi Yoshioka; Keiichirou Yamaguchi; Kazuo Kubota; Toshiyuki Saginoya; Tetsuro Yamazaki; Tatuo Ido; Gengo Yamaura; Hiromu Takahashi; Hiroshi Fukuda; Ryunosuke Kanamaru
Journal:  J Nucl Med       Date:  2003-05       Impact factor: 10.057

9.  Capecitabine and oxaliplatin for advanced esophagogastric cancer.

Authors:  David Cunningham; Naureen Starling; Sheela Rao; Timothy Iveson; Marianne Nicolson; Fareeda Coxon; Gary Middleton; Francis Daniel; Jacqueline Oates; Andrew Richard Norman
Journal:  N Engl J Med       Date:  2008-01-03       Impact factor: 91.245

10.  Gene-related cancer spectrum in families with hereditary non-polyposis colorectal cancer (HNPCC).

Authors:  Johanne Geary; Peter Sasieni; Richard Houlston; Louise Izatt; Ros Eeles; Stewart J Payne; Samantha Fisher; Shirley V Hodgson
Journal:  Fam Cancer       Date:  2007-10-16       Impact factor: 2.375

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