| Literature DB >> 20543975 |
William J Powers, Allyson R Zazulia.
Abstract
Investigation of the interplay between the cerebral circulation and brain cellular function is fundamental to understanding both the pathophysiology and treatment of stroke. Currently, PET is the only technique that provides accurate, quantitative in vivo regional measurements of both cerebral circulation and cellular metabolism in human subjects. We review normal human cerebral blood flow and metabolism and human PET studies of ischemic stroke, carotid artery disease, vascular dementia, intracerebral hemorrhage and aneurysmal subarachnoid hemorrhage and discuss how these studies have added to our understanding of the pathophysiology of human cerebrovascular disease.Entities:
Year: 2010 PMID: 20543975 PMCID: PMC2883245 DOI: 10.1016/j.cpet.2009.12.007
Source DB: PubMed Journal: PET Clin ISSN: 1556-8598