Literature DB >> 20541695

LKB1 and Src: antagonistic regulators of tumor growth and metastasis.

Jill Slack-Davis1, John O Dasilva, Sarah J Parsons.   

Abstract

In this issue of Cancer Cell, Carretero and colleagues report that Src and FAK signaling pathways are activated in lung cancers when the tumor suppressor LKB1 is deleted. These findings suggest the use of unique combinatorial therapies for treatment of lung cancers. Copyright 2010 Elsevier Inc. All rights reserved.

Entities:  

Year:  2010        PMID: 20541695     DOI: 10.1016/j.ccr.2010.05.016

Source DB:  PubMed          Journal:  Cancer Cell        ISSN: 1535-6108            Impact factor:   31.743


  4 in total

Review 1.  Targeting the LKB1 tumor suppressor.

Authors:  Rui-Xun Zhao; Zhi-Xiang Xu
Journal:  Curr Drug Targets       Date:  2014-01       Impact factor: 3.465

Review 2.  LKB1: Can We Target an Hidden Target? Focus on NSCLC.

Authors:  Gloriana Ndembe; Ilenia Intini; Elisa Perin; Mirko Marabese; Elisa Caiola; Paolo Mendogni; Lorenzo Rosso; Massimo Broggini; Marika Colombo
Journal:  Front Oncol       Date:  2022-05-11       Impact factor: 5.738

3.  Lung Cancer: Are we up to the Challenge?

Authors:  Luca Esposito; Daniele Conti; Ramyasri Ailavajhala; Nansie Khalil; Antonio Giordano
Journal:  Curr Genomics       Date:  2010-11       Impact factor: 2.236

Review 4.  Par-3 family proteins in cell polarity & adhesion.

Authors:  Barry J Thompson
Journal:  FEBS J       Date:  2021-03-03       Impact factor: 5.622

  4 in total

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