| Literature DB >> 20541530 |
Bianjiang Liu1, Wei Zhang, Zengjun Wang.
Abstract
Voltage-dependent anion channel (VDAC) is a multi-functional channel protein in the mitochondrial outer membrane of all eukaryotes. It is involved in extensive physiological and pathophysiological processes. However there is only scant information about VDAC in mammalian reproduction, fertility and development in the past. It is now recognized through recent studies that VDAC is present in male mammalian germinal tissues and cells, and plays crucial roles in spermatogenesis, sperm maturation and fertilization. This review will discuss the presence, localization and function of VDAC in mammalian spermatozoa. Copyright 2010 Elsevier Inc. All rights reserved.Entities:
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Year: 2010 PMID: 20541530 DOI: 10.1016/j.bbrc.2010.06.025
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN: 0006-291X Impact factor: 3.575