Literature DB >> 20541473

Penile ischemic injury in the exstrophy/epispadias spectrum: new insights and possible mechanisms.

Raimondo M Cervellione1, Douglas A Husmann, Trinity J Bivalacqua, Paul D Sponseller, John P Gearhart.   

Abstract

OBJECTIVE: Partial or complete penile loss following bladder exstrophy and/or epispadias repair has been reported in the literature progressively more frequently. PATIENTS AND METHODS: The authors report new cases of penile injury following bladder exstrophy and/or epispadias repair referred to their centers and not previously published. They review the literature on this subject and offer an explanation as to the likely mechanism for the penile injury and recommendations to avoid this complication.
RESULTS: Seven new cases of partial or complete penile loss following bladder exstrophy or epispadias repair have been recently referred to the authors' institutions. Twenty-one patients have previously been reported in the literature. Altogether, 24 cases occurred after bladder exstrophy closure: 23 after complete primary repair of exstrophy (Mitchell repair) and one after first-stage radical soft-tissue mobilization (Kelly repair). Nineteen of 24 patients did not have a pelvic osteotomy at the time of primary closure. Four cases occurred after epispadias repair: two following the second-stage radical soft-tissue mobilization (Kelly repair) and two following penile disassembly epispadias repair (Mitchell repair).
CONCLUSION: Exstrophy closure combined with epispadias repair can be followed by ischemic penile injury, particularly when osteotomy is not performed. Compression of the pudendal vessels after pubic apposition and/or direct injury to the pudendal vessels play an important role in the pathogenesis of this complication.
Copyright © 2010 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved.

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Year:  2010        PMID: 20541473     DOI: 10.1016/j.jpurol.2010.04.007

Source DB:  PubMed          Journal:  J Pediatr Urol        ISSN: 1477-5131            Impact factor:   1.830


  3 in total

Review 1.  [Epispadias and urethral duplication].

Authors:  A-K Ebert; K Adamczyk
Journal:  Urologe A       Date:  2015-05       Impact factor: 0.639

2.  A Model for Sustained Collaboration to Address the Unmet Global Burden of Bladder Exstrophy-Epispadias Complex and Penopubic Epispadias: The International Bladder Exstrophy Consortium.

Authors:  Rakesh S Joshi; Dhirendra Shrivastava; Richard Grady; Anjana Kundu; Jaishri Ramji; Pramod P Reddy; Joao Luiz Pippi-Salle; Jennifer R Frazier; Douglas A Canning; Aseem R Shukla
Journal:  JAMA Surg       Date:  2018-07-01       Impact factor: 14.766

3.  Kelly procedure for exstrophy or epispadias patients: Anatomical description of the pudendal neurovasculature.

Authors:  Jacob Ben-Chaim; Guy Hidas; Jamie Wikenheiser; Ezekiel H Landau; Elias Wehbi; Maryellen S Kelly; Gordon A McLorie; Antoine E Khoury
Journal:  J Pediatr Urol       Date:  2016-02-01       Impact factor: 1.830

  3 in total

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