Literature DB >> 20539314

Incidence of neovascularization in the fellow eye of patients with unilateral retinal angiomatous proliferation.

C Campa1, S P Harding, I A Pearce, N A V Beare, M C Briggs, H Heimann.   

Abstract

AIMS: The aim of this study is to describe the incidence and characteristics of neovascularization in the fellow eye of patients with retinal angiomatous proliferation (RAP).
METHODS: This is a retrospective study conducted on all patients with a diagnosis of unilateral RAP commencing treatment in a single centre between November 2002 and January 2010. Clinical biomicroscopic examination, fluorescein angiography, and if required, indocyanine green angiography, and optical coherence tomography were used to evaluate all patients.
RESULTS: In all, 37 patients had a follow-up of ≥1 year, 28 ≥2 years, and 11 ≥3. Patients who developed RAP in the fellow eye were: 2 of 37 (5.4%) within 1 year of follow-up, 4 of 28 (14.2%) within 2 years, and 4 of 11 (36.3%) within 3 years.
CONCLUSION: In our case series, the risk of neovascularization in the fellow eye of patients with unilateral RAP increased with time. Approximately one-third of patients with a 3-year follow-up developed a bilateral disease. Our findings warrant further large-scale investigation.

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Year:  2010        PMID: 20539314     DOI: 10.1038/eye.2010.88

Source DB:  PubMed          Journal:  Eye (Lond)        ISSN: 0950-222X            Impact factor:   3.775


  3 in total

Review 1.  Strategies for improving early detection and diagnosis of neovascular age-related macular degeneration.

Authors:  Pearse A Keane; Gabriella de Salvo; Dawn A Sim; Srini Goverdhan; Rupesh Agrawal; Adnan Tufail
Journal:  Clin Ophthalmol       Date:  2015-02-17

2.  Treatment of Bilateral Retinal Angiomatous Proliferation with Anti-vascular Endothelial Growth Factor: 12-Month Outcome.

Authors:  Jae Min Kim; Jae Hui Kim; Young Suk Chang; Jong Woo Kim; Chul Gu Kim; Dong Won Lee
Journal:  Korean J Ophthalmol       Date:  2017-04-24

3.  Unaffected fellow eye neovascularization in patients with type 3 neovascularization: Incidence and risk factors.

Authors:  Jae Hyuck Kwak; Woo Kyung Park; Rae Young Kim; Mirinae Kim; Young-Gun Park; Young-Hoon Park
Journal:  PLoS One       Date:  2021-07-19       Impact factor: 3.240

  3 in total

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