OBJECTIVE: This study evaluates surgical outcomes in patients with balloon cell containing, focal cortical dysplasia (FCD type IIB) in the peri-rolandic region. We also address the question of, postoperative seizure worsening after an incomplete resection in this patient population. METHODS: We retrospectively reviewed the clinical data on patients with pathologically proven FCD, who underwent epilepsy surgery over a 12-year period. Seizure outcomes were compared between, patients with rolandic FCD and non-rolandic frontal FCD. RESULTS: Seventeen patients with rolandic and 22 patients with non-rolandic FCD were identified. Twelve patients were found to have type IIB lesions (8 rolandic). Seizure freedom at last follow up was, achieved in 59% of the rolandic subset of patients (including 75% seizure freedom in the rolandic type, IIB cases, as opposed to 44% of rolandic non-type IIB and 75% of type IIB outside the rolandic, region). New postoperative neurological deficits occurred in 59% of the rolandic subgroup and were, independent of pathology. Three patients (3/8) with incompletely resected rolandic type IIB lesions, developed status epilepticus postoperatively; all 3 patients became seizure free following a second, more extensive surgical resection. CONCLUSIONS: Patients with rolandic FCD can achieve a good surgical outcome after a complete, resection. However, an incomplete surgical resection in this patient population may lead to acute, postoperative seizure worsening.
OBJECTIVE: This study evaluates surgical outcomes in patients with balloon cell containing, focal cortical dysplasia (FCD type IIB) in the peri-rolandic region. We also address the question of, postoperative seizure worsening after an incomplete resection in this patient population. METHODS: We retrospectively reviewed the clinical data on patients with pathologically proven FCD, who underwent epilepsy surgery over a 12-year period. Seizure outcomes were compared between, patients with rolandic FCD and non-rolandic frontal FCD. RESULTS: Seventeen patients with rolandic and 22 patients with non-rolandic FCD were identified. Twelve patients were found to have type IIB lesions (8 rolandic). Seizure freedom at last follow up was, achieved in 59% of the rolandic subset of patients (including 75% seizure freedom in the rolandic type, IIB cases, as opposed to 44% of rolandic non-type IIB and 75% of type IIB outside the rolandic, region). New postoperative neurological deficits occurred in 59% of the rolandic subgroup and were, independent of pathology. Three patients (3/8) with incompletely resected rolandic type IIB lesions, developed status epilepticus postoperatively; all 3 patients became seizure free following a second, more extensive surgical resection. CONCLUSIONS:Patients with rolandic FCD can achieve a good surgical outcome after a complete, resection. However, an incomplete surgical resection in this patient population may lead to acute, postoperative seizure worsening.
Authors: Claire Haegelen; Piero Perucca; Claude-Edouard Châtillon; Luciana Andrade-Valença; Rina Zelmann; Julia Jacobs; D Louis Collins; François Dubeau; André Olivier; Jean Gotman Journal: Epilepsia Date: 2013-01-07 Impact factor: 5.864
Authors: A Simon Harvey; Simone A Mandelstam; Wirginia J Maixner; Richard J Leventer; Mira Semmelroch; Duncan MacGregor; Renate M Kalnins; Yuliya Perchyonok; Gregory J Fitt; Sarah Barton; Michael J Kean; Gavin C A Fabinyi; Graeme D Jackson Journal: Neurology Date: 2015-04-17 Impact factor: 9.910
Authors: Matthew F Sacino; Cheng-Ying Ho; Matthew T Whitehead; Tesfaye Zelleke; Suresh N Magge; John Myseros; Robert F Keating; William D Gaillard; Chima O Oluigbo Journal: Childs Nerv Syst Date: 2016-04-05 Impact factor: 1.475