Literature DB >> 20537549

Junctional ectopic tachycardia after surgery for congenital heart disease: incidence, risk factors and outcome.

Leena Mildh1, Anita Hiippala, Paula Rautiainen, Ville Pettilä, Heikki Sairanen, Juha-Matti Happonen.   

Abstract

OBJECTIVES: Junctional ectopic tachycardia (JET) is a serious, haemodynamically compromising tachyarrhythmia associated with paediatric cardiac surgery, with a reported mortality up to 14%. The incidence, risk factors and outcome of this tachyarrhythmia were evaluated in this population-based, case-control patient cohort.
METHODS: A total of 1001 children, who underwent open-heart surgery during a 5-year period, were retrospectively analysed. The patients with haemodynamically significant tachycardia were identified, and their postoperative electrocardiograms were analysed. Three controls matched with the same type of surgery were selected for each patient with JET.
RESULTS: JET was diagnosed in 51 patients (5.0%). These patients had longer cardiopulmonary bypass time (138 vs 119 min, p=0.002), higher body temperature (38.0 vs 37.4 °C, p=0.013) and higher level of postoperative troponin-T (3.7 vs 2.1 μg l(-1), p<0.001) compared with controls. They also needed longer ventilatory support (3 vs 2 days, p=0.004) and intensive care stay (7 vs 5 days, p<0.001) as well as use of noradrenaline (23/51 vs 35/130, p=0.019). Ventricular septal defect (VSD) closure was part of the surgery in 33/51 (64.7%) of these patients. The mortality was 8% in the JET group and 5% in the controls (p=0.066). In the logistic regression model, JET was not an independent risk factor for death (p=0.557).
CONCLUSIONS: The incidence of JET was 5.0% in this large paediatric open-heart surgery patient group. Compared with controls, these patients had longer cardiopulmonary bypass time and higher level of troponin-T, possibly reflecting the extent of surgical trauma. However, the tachycardia was not an independent risk factor for death. Copyright Â
© 2010 European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved.

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Year:  2011        PMID: 20537549     DOI: 10.1016/j.ejcts.2010.04.002

Source DB:  PubMed          Journal:  Eur J Cardiothorac Surg        ISSN: 1010-7940            Impact factor:   4.191


  22 in total

Review 1.  The changing epidemiology of congenital heart disease.

Authors:  Teun van der Bom; A Carla Zomer; Aeilko H Zwinderman; Folkert J Meijboom; Berto J Bouma; Barbara J M Mulder
Journal:  Nat Rev Cardiol       Date:  2010-11-02       Impact factor: 32.419

2.  Management of postoperative junctional ectopic tachycardia in pediatric patients: a survey of 30 centers in Germany, Austria, and Switzerland.

Authors:  Andreas Entenmann; Miriam Michel; Ulrike Herberg; Nikolaus Haas; Matthias Kumpf; Matthias Gass; Friedemann Egender; Roman Gebauer
Journal:  Eur J Pediatr       Date:  2017-07-21       Impact factor: 3.183

3.  Junctional ectopic tachycardia.

Authors:  Johnson Francis
Journal:  Indian Pacing Electrophysiol J       Date:  2010-07-20

4.  Perioperative care of a child with transposition of the great arteries.

Authors:  Angela Lorts; Catherine D Krawczeski
Journal:  Curr Treat Options Cardiovasc Med       Date:  2011-10

5.  A genetic contribution to risk for postoperative junctional ectopic tachycardia in children undergoing surgery for congenital heart disease.

Authors:  Kristie Y Borgman; Andrew H Smith; Jill P Owen; Frank A Fish; Prince J Kannankeril
Journal:  Heart Rhythm       Date:  2011-07-06       Impact factor: 6.343

6.  Isolated junctional tachycardia in a child after noncardiac surgery: an uncommon clinical presentation.

Authors:  Chenni S Sriram; Roger D White; Malini Madhavan; Bryan C Cannon
Journal:  Pediatr Cardiol       Date:  2011-08-02       Impact factor: 1.655

7.  Ivabradine Monotherapy for the Treatment of Congenital Junctional Ectopic Tachycardia in a Premature Neonate.

Authors:  Suzan S Asfour; Khalid A Al-Omran; Nabeel A Alodhaidan; Raneem S Asfour; Thanaa M Khalil; Mountasser M Al-Mouqdad
Journal:  J Pediatr Pharmacol Ther       Date:  2021-05-19

8.  Magnesium Lowers the Incidence of Postoperative Junctional Ectopic Tachycardia in Congenital Heart Surgical Patients: Is There a Relationship to Surgical Procedure Complexity?

Authors:  Dingchao He; Nathaniel Sznycer-Taub; Yao Cheng; Robert McCarter; Richard A Jonas; Sridhar Hanumanthaiah; Jeffrey P Moak
Journal:  Pediatr Cardiol       Date:  2015-03-12       Impact factor: 1.655

Review 9.  Magnesium supplementation reduces postoperative arrhythmias after cardiopulmonary bypass in pediatrics: a metaanalysis of randomized controlled trials.

Authors:  Hee Young Lee; Saurav Ghimire; Eun Young Kim
Journal:  Pediatr Cardiol       Date:  2013-02-27       Impact factor: 1.655

10.  Junctional ectopic tachycardia after congenital heart surgery in the current surgical era.

Authors:  Majd Makhoul; Matthew Oster; Peter Fischbach; Srikant Das; Shriprasad Deshpande
Journal:  Pediatr Cardiol       Date:  2012-09-18       Impact factor: 1.655

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