Literature DB >> 20532024

Alzheimer's therapies.

Elisa F Cascade1, Amir H Kalali, Edmund Howe.   

Abstract

This article investigates the role that psychiatrists play in the prescription of Alzheimer's disease therapies and the similarities and differences in treatment approach when compared to primary care physicians and neurologists. Psychiatrists account for 7.6 percent of new patient starts on Alzheimer's disease therapies. Similar to other prescribers, over 75 percent of product use by psychiatrists is for two diagnoses: 294-Other Organic Psychiatric Condition and 331-Cerebral Degeneration. The primary difference between psychiatrists and other prescribers is in the concomitant use of antipsychotics, antidepressants, and seizure disorder therapies. Specifically, psychiatrists use antipsychotics, antidepressants, and antiepileptics in combination with Alzheimer's disease therapies in 27 percent, 12 percent, and nine percent of treatment regimens, respectively. In contrast, these drug classes are used concomitantly in less than five percent of treatment regimens for patients treated by neurologists and primary care physicians. An expert commentary is provided.

Entities:  

Keywords:  Alzheimer's disease; antidepressants; antiepileptics; antipsychotics; dementia; neurology; primary care

Year:  2007        PMID: 20532024      PMCID: PMC2880950     

Source DB:  PubMed          Journal:  Psychiatry (Edgmont)        ISSN: 1550-5952


  17 in total

1.  A shift in the paradigm of treatment.

Authors:  Edmund G Howe
Journal:  Psychiatry (Edgmont)       Date:  2006-11

2.  Do we undervalue feelings in patients who are cognitively impaired?

Authors:  Edmund G Howe
Journal:  J Clin Ethics       Date:  2006

Review 3.  Recommendations for the diagnosis and management of Alzheimer's disease and other disorders associated with dementia: EFNS guideline.

Authors:  G Waldemar; B Dubois; M Emre; J Georges; I G McKeith; M Rossor; P Scheltens; P Tariska; B Winblad
Journal:  Eur J Neurol       Date:  2007-01       Impact factor: 6.089

Review 4.  A tiered model of psychogeriatric service delivery: an evidence-based approach.

Authors:  Brian Draper; Henry Brodaty; Lee-Fay Low
Journal:  Int J Geriatr Psychiatry       Date:  2006-07       Impact factor: 3.485

5.  Antipsychotic use varies by patient age.

Authors:  Elisa F Cascade; Amir H Kalali; Leslie Citrome
Journal:  Psychiatry (Edgmont)       Date:  2007-07

6.  Family caregiving in dementia--an analysis of the caregiver's burden and the "breaking-point" when home care becomes inadequate.

Authors:  L Annerstedt; S Elmståhl; B Ingvad; S M Samuelsson
Journal:  Scand J Public Health       Date:  2000-03       Impact factor: 3.021

Review 7.  Contribution of depression to cognitive impairment and dementia in older adults.

Authors:  Guy G Potter; David C Steffens
Journal:  Neurologist       Date:  2007-05       Impact factor: 1.398

Review 8.  Assessment of behavioural and psychological symptoms associated with dementia.

Authors:  David Conn; Lilian Thorpe
Journal:  Can J Neurol Sci       Date:  2007-03       Impact factor: 2.104

Review 9.  Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria.

Authors:  Bruno Dubois; Howard H Feldman; Claudia Jacova; Steven T Dekosky; Pascale Barberger-Gateau; Jeffrey Cummings; André Delacourte; Douglas Galasko; Serge Gauthier; Gregory Jicha; Kenichi Meguro; John O'brien; Florence Pasquier; Philippe Robert; Martin Rossor; Steven Salloway; Yaakov Stern; Pieter J Visser; Philip Scheltens
Journal:  Lancet Neurol       Date:  2007-08       Impact factor: 44.182

Review 10.  Depression in Alzheimer's disease: overview and treatment.

Authors:  Constantine G Lyketsos; Jason Olin
Journal:  Biol Psychiatry       Date:  2002-08-01       Impact factor: 13.382

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