Literature DB >> 20530472

Effect of HIV infection on body composition and fat distribution in Rwandan women.

Eugene Mutimura1, Kathryn Anastos, Mardge Cohen, Agnes Binagwaho, Donald P Kotler.   

Abstract

OBJECTIVE: To assess the association of HIV infection with body weight and composition in Rwandan women.
DESIGN: Body weight and composition, the latter determined by bioelectrical impedance analysis (BIA) and by anthropometry, were compared in 620 HIV-positive and 211 HIV-negative participants. Associations of HIV with body composition were assessed, and t tests compared the groups.
RESULTS: HIV-positive women were younger (-7.0 years, P < .001) and shorter (-2.1 cm, P < .001). Mean body weight, body mass index (BMI), total body fat, and waist-to-hip ratio (WHR) were similar. Mean fat-free mass was 2.5% greater in HIV-negative participants, and 19% of HIV-positive group had BMI <18.5 kg/m(2) versus 26% of the HIV-negative group (P < .05). CD4 counts and body composition were not associated.
CONCLUSIONS: Malnutrition was common in this cohort of Rwandan women. However, HIV infection was not associated with nutritional status. Factors other than malnutrition may influence quality-of-life outcomes in HIV-infected Rwandan women. Initiatives to improve nutritional status should be population-wide and not restricted to the HIV-infected population.

Entities:  

Mesh:

Year:  2010        PMID: 20530472      PMCID: PMC4460979          DOI: 10.1177/1545109710366472

Source DB:  PubMed          Journal:  J Int Assoc Physicians AIDS Care (Chic)        ISSN: 1545-1097


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