Literature DB >> 20529098

Outcomes of surgical repair of bile leaks and strictures after adult-to-adult living donor liver transplant.

Marc L Melcher1, Chris E Freise, Nancy L Ascher, John P Roberts.   

Abstract

UNLABELLED: We sought to determine factors that predict the successful surgical repair of biliary complications after adult living donor liver transplantation (ALDLT).
METHODS: Records of 82 consecutive ALDLT right lobe recipients were reviewed. Operations were performed on 19 recipients for biliary complications. Post-operative biliary complications were analyzed. Fisher's exact test was used to identify variables that correlated with successful surgical repair.
RESULTS: A total of 29 recipients had biliary complications, of which 19 had a surgical repair. The five recipients, operated on for a stricture without history of leaks, did not develop further complications. However, nine of 14 with a history of a leak developed further complications after surgical repair (p-value = 0.044). All five who presented with a biliary complication more than 100 d after transplant had successful surgical repair; however, nine out of 13 who presented within 57 d had additional complications after repair.
CONCLUSIONS: Operations for strictures after ALDLT are more successful than operations for leaks. Recipients with isolated biliary strictures after ALDLT can be managed surgically; however, recipients with history of a leak often require additional interventions after surgical repair.
© 2010 John Wiley & Sons A/S.

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Year:  2010        PMID: 20529098     DOI: 10.1111/j.1399-0012.2010.01289.x

Source DB:  PubMed          Journal:  Clin Transplant        ISSN: 0902-0063            Impact factor:   2.863


  2 in total

Review 1.  Biliary complications in right lobe living donor liver transplantation.

Authors:  Kenneth S H Chok; Chung Mau Lo
Journal:  Hepatol Int       Date:  2016-03-01       Impact factor: 6.047

2.  Non-surgical treatment of post-surgical bile duct injury: clinical implications and outcomes.

Authors:  Young Ook Eum; Joo Kyung Park; Jaeyoung Chun; Sang-Hyub Lee; Ji Kon Ryu; Yong-Tae Kim; Yong-Bum Yoon; Chang Jin Yoon; Ho-Seong Han; Jin-Hyeok Hwang
Journal:  World J Gastroenterol       Date:  2014-06-14       Impact factor: 5.742

  2 in total

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