Literature DB >> 20528837

A comparison of the effect on QT interval between thiamylal and propofol during anaesthetic induction*.

U Higashijima1, Y Terao, T Ichinomiya, K Miura, M Fukusaki, K Sumikawa.   

Abstract

SUMMARY: The aim of this study was to determine the effect of thiamylal and propofol on heart rate-corrected QT (QTc) interval during anaesthetic induction. We studied 50 patients undergoing lumbar spine surgery. Patients were administered 3 microgxkg(-1) fentanyl and were randomly allocated to receive 5 mgxkg(-1) thiamylal or 1.5 mgxkg(-1) propofol as an induction agent. Tracheal intubation was performed after vecuronium administration. Heart rate, mean arterial pressure, bispectral index score, and 12-lead electrocardiogram were recorded at the following time points: just before (T1) and 2 min after (T2) fentanyl administration; 2 min after anaesthetic administration (T3); 2.5 min after vecuronium injection (T4); and 2 min after intubation (T5). Thiamylal prolonged (p < 0.0001), but propofol shortened (p < 0.0001), the QTc interval.

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Year:  2010        PMID： 20528837     DOI： 10.1111/j.1365-2044.2010.06341.x

Source DB:  PubMed          Journal:  Anaesthesia        ISSN： 0003-2409            Impact factor:   6.955


  9 in total

1.  QTc interval and neurological outcomes in aneurysmal subarachnoid hemorrhage.

Authors:  Taiga Ichinomiya; Yoshiaki Terao; Kosuke Miura; Ushio Higashijima; Tomomi Tanise; Makoto Fukusaki; Koji Sumikawa
Journal:  Neurocrit Care       Date:  2010-12       Impact factor: 3.210

2.  Differential effects of propofol and sevoflurane on QT interval during anesthetic induction.

Authors:  Makito Oji; Yoshiaki Terao; Tomomi Toyoda; Tomoyuki Kuriyama; Kosuke Miura; Makoto Fukusaki; Koji Sumikawa
Journal:  J Clin Monit Comput       Date:  2012-12-15       Impact factor: 2.502

3.  Drugs to be avoided in patients with long QT syndrome: Focus on the anaesthesiological management.

Authors:  Giovanni Fazio; Federica Vernuccio; Giuseppe Grutta; Giuseppe Lo Re
Journal:  World J Cardiol       Date:  2013-04-26

4.  The effects of intravenous anesthetics on QT interval during anesthetic induction with sevoflurane.

Authors:  Yoshiaki Terao; Ushio Higashijima; Tomomi Toyoda; Taiga Ichinomiya; Makoto Fukusaki; Tetsuya Hara
Journal:  J Anesth       Date:  2016-09-21       Impact factor: 2.078

5.  Propofol-associated QTc prolongation.

Authors:  Michael J Scalese; Holly R Herring; R Chris Rathbun; Grant H Skrepnek; Toni L Ripley
Journal:  Ther Adv Drug Saf       Date:  2016-04-01

6.  The interaction of antiemetic dose of droperidol with propofol on QT interval during anesthetic induction.

Authors:  Tomomi Toyoda; Yoshiaki Terao; Makito Oji; Mai Okada; Makoto Fukusaki; Koji Sumikawa
Journal:  J Anesth       Date:  2013-05-10       Impact factor: 2.078

7.  A Comparison of the Effect of Sevoflurane and Propofol on Ventricular Repolarisation after Preoperative Cefuroxime Infusion.

Authors:  Yanqiu Liu; Hong Gao; Guilong Wang; Li An; Jing Yi; Xiaokui Fu; Chunlei Wen; Zijun Wang
Journal:  Biomed Res Int       Date:  2019-01-02       Impact factor: 3.411

8.  The effects of intravenous anesthetics on QT interval during anesthetic induction with desflurane.

Authors:  Shozo Tominaga; Yoshiaki Terao; Shigehiko Urabe; Maki Ono; Natsuko Oji; Makito Oji; Makoto Fukusaki; Tetsuya Hara
Journal:  JA Clin Rep       Date:  2018-07-30

9.  Propofol prevents further prolongation of QT interval during liver transplantation.

Authors:  Seung Hyun Kim; Jae Geun Lee; Hyang Mi Ju; SuYoun Choi; Hyukjin Yang; Bon-Nyeo Koo
Journal:  Sci Rep       Date:  2022-03-17       Impact factor: 4.379
  9 in total

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