Literature DB >> 20528816

Alcohol use and non-adherence to antiretroviral therapy in HIV-infected patients in West Africa.

Antoine Jaquet1, Didier K Ekouevi, Jules Bashi, Maiga Aboubakrine, Eugène Messou, Moussa Maiga, Hamar Alassane Traore, Marcel Djimon Zannou, Calixte Guehi, Franck Olivier Ba-Gomis, Albert Minga, Gérard Allou, Serge Paul Eholie, Emmanuel Bissagnene, Annie J Sasco, Francois Dabis.   

Abstract

AIM: To investigate the association between alcohol use and adherence to highly active antiretroviral treatment (HAART) among human immunodeficiency virus (HIV)-infected patients in sub-Saharan Africa. DESIGN AND
SETTING: Cross-sectional survey conducted in eight adult HIV treatment centres from Benin, Côte d'Ivoire and Mali. Participants and measurements During a 4-week period, health workers administered the Alcohol Use Disorders Identification Test to HAART-treated patients and assessed treatment adherence using the AIDS Clinical Trials Group follow-up questionnaire.
FINDINGS: A total of 2920 patients were enrolled with a median age of 38 years [interquartile range (IQR) 32-45 years] and a median duration on HAART of 3 years (IQR 1-4 years). Overall, 91.8% of patients were identified as adherent to HAART. Non-adherence was associated with current drinking [odds ratio (OR) 1.4; 95% confidence interval (CI) 1.1-2.0], hazardous drinking (OR 4.7; 95% CI 2.6-8.6) and was associated inversely with a history of counselling on adherence (OR 0.7; 95% CI 0.5-0.9).
CONCLUSIONS: Alcohol consumption and hazardous drinking is associated with non-adherence to HAART among HIV-infected patients from West Africa. Adult HIV care programmes should integrate programmes to reduce hazardous and harmful drinking.

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Year:  2010        PMID: 20528816      PMCID: PMC4458514          DOI: 10.1111/j.1360-0443.2010.02978.x

Source DB:  PubMed          Journal:  Addiction        ISSN: 0965-2140            Impact factor:   6.526


  23 in total

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Journal:  AIDS       Date:  2003-07       Impact factor: 4.177

2.  Adherence is not a barrier to successful antiretroviral therapy in South Africa.

Authors:  Catherine Orrell; David R Bangsberg; Motasim Badri; Robin Wood
Journal:  AIDS       Date:  2003-06-13       Impact factor: 4.177

3.  A prospective study of adherence and viral load in a large multi-center cohort of HIV-infected women.

Authors:  Andrea A Howard; Julia H Arnsten; Yungtai Lo; David Vlahov; Josiah D Rich; Paula Schuman; Valerie E Stone; Dawn K Smith; Ellie E Schoenbaum
Journal:  AIDS       Date:  2002-11-08       Impact factor: 4.177

4.  Self-reported adherence to antiretroviral medications among participants in HIV clinical trials: the AACTG adherence instruments. Patient Care Committee & Adherence Working Group of the Outcomes Committee of the Adult AIDS Clinical Trials Group (AACTG).

Authors:  M A Chesney; J R Ickovics; D B Chambers; A L Gifford; J Neidig; B Zwickl; A W Wu
Journal:  AIDS Care       Date:  2000-06

5.  Field adherence to highly active antiretroviral therapy in HIV-infected adults in Abidjan, Côte d'Ivoire.

Authors:  Serge-Paul Eholié; Aristophane Tanon; Sandrine Polneau; Mariama Ouiminga; Ayoman Djadji; Constance Kangah-Koffi; Nafissatou Diakité; Xavier Anglaret; Aka Kakou; Emmanuel Bissagnené
Journal:  J Acquir Immune Defic Syndr       Date:  2007-07-01       Impact factor: 3.731

6.  Longitudinal assessment of the effects of drug and alcohol abuse on HIV-1 treatment outcomes in an urban clinic.

Authors:  Gregory M Lucas; Kelly A Gebo; Richard E Chaisson; Richard D Moore
Journal:  AIDS       Date:  2002-03-29       Impact factor: 4.177

7.  Determinants of heterogeneous adherence to HIV-antiretroviral therapies in the Multicenter AIDS Cohort Study.

Authors:  C A Kleeberger; J P Phair; S A Strathdee; R Detels; L Kingsley; L P Jacobson
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8.  Alcohol problems among patients attending five primary health care clinics in Harare city.

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9.  The Alcohol Use Disorders Identification Test (AUDIT): validation of a screening instrument for use in medical settings.

Authors:  M J Bohn; T F Babor; H R Kranzler
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10.  Determinants of unplanned antiretroviral treatment interruptions among people living with HIV in Yaoundé, Cameroon (EVAL survey, ANRS 12-116).

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Journal:  Trop Med Int Health       Date:  2008-11-05       Impact factor: 2.622

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2.  Return to normal life after AIDS as a reason for lost to follow-up in a community-based antiretroviral treatment program.

Authors:  Stella T Alamo; Robert Colebunders; Joseph Ouma; Pamela Sunday; Glenn Wagner; Fred Wabwire-Mangen; Marie Laga
Journal:  J Acquir Immune Defic Syndr       Date:  2012-06-01       Impact factor: 3.731

3.  Changes in Days of Unhealthy Alcohol Use and Antiretroviral Therapy Adherence, HIV RNA Levels, and Condomless Sex: A Secondary Analysis of Clinical Trial Data.

Authors:  Derek D Satre; Varada Sarovar; Wendy Leyden; Charles B Hare; Sheryl L Catz; Kendall J Bryant; Emily C Williams; J Carlo Hojilla; Michael A Horberg; Michael J Silverberg
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4.  Correlates of non-adherence to antiretroviral therapy in a cohort of HIV-positive drug users receiving antiretroviral therapy in Hanoi, Vietnam.

Authors:  M R Jordan; Y Obeng-Aduasare; H Sheehan; S Y Hong; N Terrin; D V Duong; N V Trung; C Wanke; N V Kinh; A M Tang
Journal:  Int J STD AIDS       Date:  2013-12-18       Impact factor: 1.359

5.  Alcohol use and immune reconstitution among HIV-infected patients on antiretroviral therapy in Nairobi, Kenya.

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6.  Alcohol and drug use outcomes among vulnerable women living with HIV: results from the Western Cape Women's Health CoOp.

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Review 7.  Adding fuel to the fire: alcohol's effect on the HIV epidemic in Sub-Saharan Africa.

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8.  REVIEW OF DENTISTRY IN WEST AFRICA- CHALLENGES AND PROSPECTS.

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9.  Barriers to HIV Treatment Adherence: A Qualitative Study of Discrepancies Between Perceptions of Patients and Health Providers in Tanzania and Uganda.

Authors:  Corrina Moucheraud; Amy F Stern; Canice Ahearn; Anisa Ismail; Tamara Nsubuga-Nyombi; Monica M Ngonyani; Jane Mvungi; Jude Ssensamba
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Review 10.  The Impact of Alcohol Use and Related Disorders on the HIV Continuum of Care: a Systematic Review : Alcohol and the HIV Continuum of Care.

Authors:  Panagiotis Vagenas; Marwan M Azar; Michael M Copenhaver; Sandra A Springer; Patricia E Molina; Frederick L Altice
Journal:  Curr HIV/AIDS Rep       Date:  2015-12       Impact factor: 5.071

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