| Literature DB >> 20528472 |
Ortwin Adams1, Linda Bonzel, Alexander Kovacevic, Ertan Mayatepek, Thomas Hoehn, Markus Vogel.
Abstract
Palivizumab-resistant respiratory syncytial virus was isolated from an infant treated with palivizumab. A stable mutation at codon 276 led to a nearly complete resistance to palivizumab. Additional studies revealed a second mutation at codon 272. Further passage of the virus led to a complete loss of binding of palivizumab.Entities:
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Year: 2010 PMID: 20528472 DOI: 10.1086/653534
Source DB: PubMed Journal: Clin Infect Dis ISSN: 1058-4838 Impact factor: 9.079