B Mossa1, F Torcia, F Avenoso, S Tucci, R Marziani. 1. Department of Gynaecology, Perinatology and Child Health, Sapienza University, Rome, Italy. bruno.mossa@uniroma1.it
Abstract
OBJECTIVE: To evaluate the occurrence of endometrial polyp malignancy in pre- and postmenopausal women with or without symptoms. MATERIALS AND METHODS: A retrospective study was performed on 351 patients with endometrial polyps diagnosed by hysteroscopy. RESULTS: Histological findings of biopsies obtained by operative hysteroscopy confirmed the presence of a simple endometrial polyp in 179 cases, polyps with typical simple hyperplasia in 42 cases, polyps with typical complex hyperplasia in 24 cases, polyps with atypical complex hyperplasia in three cases; carcinomatous polyps in seven cases; atrophic polyps in 17 cases; functional polyps in 56 cases; and inadequate sample in 23 cases. All seven patients with adenocarcinoma were symptomatic; six out of seven patients with adenocarcinoma were in postmenopause and one was in premenopause. The association between menopausal status and symptoms, and the presence of a malignant lesion was statistically significant (p < 0.001). CONCLUSIONS: This study revealed that prevalence of endometrial polyp malignant transformation was < or = 2.84% in postmenopausal and symptomatic patients.
OBJECTIVE: To evaluate the occurrence of endometrial polyp malignancy in pre- and postmenopausal women with or without symptoms. MATERIALS AND METHODS: A retrospective study was performed on 351 patients with endometrial polyps diagnosed by hysteroscopy. RESULTS: Histological findings of biopsies obtained by operative hysteroscopy confirmed the presence of a simple endometrial polyp in 179 cases, polyps with typical simple hyperplasia in 42 cases, polyps with typical complex hyperplasia in 24 cases, polyps with atypical complex hyperplasia in three cases; carcinomatous polyps in seven cases; atrophic polyps in 17 cases; functional polyps in 56 cases; and inadequate sample in 23 cases. All seven patients with adenocarcinoma were symptomatic; six out of seven patients with adenocarcinoma were in postmenopause and one was in premenopause. The association between menopausal status and symptoms, and the presence of a malignant lesion was statistically significant (p < 0.001). CONCLUSIONS: This study revealed that prevalence of endometrial polyp malignant transformation was < or = 2.84% in postmenopausal and symptomatic patients.
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