Literature DB >> 20527065

Osteoporosis: Serotonin biosynthesis block builds bone.

Sarah Crunkhorn.   

Abstract

Entities:  

Year:  2010        PMID： 20527065     DOI： 10.1038/nrd3142

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


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  2 in total

1.  Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis.

Authors:  Vijay K Yadav; Santhanam Balaji; Padmanaban S Suresh; X Sherry Liu; Xin Lu; Zhishan Li; X Edward Guo; J John Mann; Anil K Balapure; Michael D Gershon; Rudraiah Medhamurthy; Marc Vidal; Gerard Karsenty; Patricia Ducy
Journal:  Nat Med       Date:  2010-02-07       Impact factor: 53.440

2.  Discovery and characterization of novel tryptophan hydroxylase inhibitors that selectively inhibit serotonin synthesis in the gastrointestinal tract.

Authors:  Qingyun Liu; Qi Yang; Weimei Sun; Pete Vogel; William Heydorn; Xiang-Qing Yu; Zhixiang Hu; Wangsheng Yu; Brandie Jonas; Randy Pineda; Valerie Calderon-Gay; Michael Germann; Emily O'Neill; Robert Brommage; Emily Cullinan; Ken Platt; Alan Wilson; Dave Powell; Arthur Sands; Brian Zambrowicz; Zhi-Cai Shi
Journal:  J Pharmacol Exp Ther       Date:  2008-01-11       Impact factor: 4.030
  2 in total

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