OBJECTIVES: To determine the relationship between body mass index (BMI), homeostasis model assessment insulin resistance (HOMA-IR) and insulinemia. METHODS: This was a prospective cross-sectional observational study of 132 prepubescent schoolchildren residents in the municipality of Santo André, Brazil. Children underwent anthropometric assessment, their glycemia and insulinemia were measured and their HOMA-IR index calculated. RESULTS: Seventy-eight of the 132 children (59.1%) were girls and 54 were boys (40.9%), with a mean age of 8.7 years and mean BMI of 13.7 kg/m(2). A significant positive association was detected between HOMA-IR and BMI, insulin and BMI, weight and HOMA and between insulin and weight. It was also found that the higher the BMI, the greater the HOMA score. CONCLUSIONS: The results of this study allow for the conclusion that there is a strong association between hyperinsulinism and obesity. Measures should be taken to avoid weight gain during childhood and adolescence.
OBJECTIVES: To determine the relationship between body mass index (BMI), homeostasis model assessment insulin resistance (HOMA-IR) and insulinemia. METHODS: This was a prospective cross-sectional observational study of 132 prepubescent schoolchildren residents in the municipality of Santo André, Brazil. Children underwent anthropometric assessment, their glycemia and insulinemia were measured and their HOMA-IR index calculated. RESULTS: Seventy-eight of the 132 children (59.1%) were girls and 54 were boys (40.9%), with a mean age of 8.7 years and mean BMI of 13.7 kg/m(2). A significant positive association was detected between HOMA-IR and BMI, insulin and BMI, weight and HOMA and between insulin and weight. It was also found that the higher the BMI, the greater the HOMA score. CONCLUSIONS: The results of this study allow for the conclusion that there is a strong association between hyperinsulinism and obesity. Measures should be taken to avoid weight gain during childhood and adolescence.
Authors: Heloísa Marcelina da Cunha Palhares; Adriana Paula da Silva; Daniela Cristina Silva Resende; Gilberto de Araújo Pereira; Virmondes Rodrigues; Maria de Fátima Borges Journal: Clinics (Sao Paulo) Date: 2017-01-01 Impact factor: 2.365
Authors: Maria Izabel Siqueira de Andrade; Juliana Souza Oliveira; Vanessa Sá Leal; Niedja Maria da Silva Lima; Emília Chagas Costa; Nathalia Barbosa de Aquino; Pedro Israel Cabral de Lira Journal: Rev Paul Pediatr Date: 2015-10-20
Authors: Heloísa Marcelina da Cunha Palhares; Paula Cunha Zaidan; Fernanda Cristina Mattos Dib; Adriana Paula da Silva; Daniela Cristina Silva Resende; Maria de Fátima Borges Journal: Rev Paul Pediatr Date: 2018 Jul-Sep