OBJECTIVE: To report the surgical experience in the management of patients with synchronous primary lung cancer and solitary brain metastasis. DESIGN: Retrospective cohort study. SETTING: Regional hospital, Hong Kong. PATIENTS: Seventeen patients with synchronous primary lung cancer and solitary brain metastasis were treated by pulmonary resection and neurosurgical intervention between 1994 and 2007. RESULTS: Median patient survival was 52 months (95% confidence interval, 9-95 months) and the 5-year survival was 27%. The univariate analysis yielded no significant prognostic factor. Four out of six patients who had lymph node metastases developed tumour recurrence. CONCLUSION: In view of encouraging survival results, aggressive therapy including pulmonary resection and neurosurgical intervention should be recommended for patients with synchronous presentation with primary lung cancer and solitary brain metastasis.
OBJECTIVE: To report the surgical experience in the management of patients with synchronous primary lung cancer and solitary brain metastasis. DESIGN: Retrospective cohort study. SETTING: Regional hospital, Hong Kong. PATIENTS: Seventeen patients with synchronous primary lung cancer and solitary brain metastasis were treated by pulmonary resection and neurosurgical intervention between 1994 and 2007. RESULTS: Median patient survival was 52 months (95% confidence interval, 9-95 months) and the 5-year survival was 27%. The univariate analysis yielded no significant prognostic factor. Four out of six patients who had lymph node metastases developed tumour recurrence. CONCLUSION: In view of encouraging survival results, aggressive therapy including pulmonary resection and neurosurgical intervention should be recommended for patients with synchronous presentation with primary lung cancer and solitary brain metastasis.
Authors: Imre Varga; Gábor Hutóczki; Csaba D Szemcsák; Gábor Zahuczky; Judit Tóth; Zsolt Adamecz; Annamária Kenyeres; László Bognár; Zoltán Hanzély; Almos Klekner Journal: Pathol Oncol Res Date: 2011-10-14 Impact factor: 3.201
Authors: Phillip J Gray; Raymond H Mak; Beow Y Yeap; Sarah K Cryer; Nancy E Pinnell; Laura W Christianson; David J Sher; Nils D Arvold; Elizabeth H Baldini; Aileen B Chen; David E Kozono; Scott J Swanson; David M Jackman; Brian M Alexander Journal: Lung Cancer Date: 2014-06-06 Impact factor: 5.705
Authors: John Nikitas; Michael Roach; Cliff Robinson; Jeffrey Bradley; Jiayi Huang; Stephanie Perkins; Christina Tsien; Christopher Abraham Journal: Clin Transl Radiat Oncol Date: 2019-12-11