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Literature DB >> 20519116

Autophagy: a potential link between obesity and insulin resistance.

Abstract

Dysregulation of autophagy contributes to aging and to diseases such as neurodegeneration, cardiomyopathy, and cancer. The paper by Yang et al. (2010) in this issue of Cell Metabolism indicates that defective autophagy may also underlie impaired insulin sensitivity in obesity and that upregulating autophagy can combat insulin resistance. Copyright 2010 Elsevier Inc. All rights reserved.

Entities: Disease Gene

Year: 2010 PMID： 20519116 DOI： 10.1016/j.cmet.2010.05.006

Source DB: PubMed Journal: Cell Metab ISSN： 1550-4131 Impact factor: 27.287

Keyword Cloud
Cited

41 in total

1. Markers of autophagy are adapted to hyperglycaemia in skeletal muscle in type 2 diabetes.

Authors: Rikke Kruse; Birgitte F Vind; Stine J Petersson; Jonas M Kristensen; Kurt Højlund
Journal: Diabetologia Date: 2015-06-07 Impact factor: 10.122

Review 2. Autophagy regulates insulin resistance following endoplasmic reticulum stress in diabetes.

Authors: Ning Zhang; Ming-ming Cao; Han Liu; Guang-ying Xie; Yan-bo Li
Journal: J Physiol Biochem Date: 2015-01-30 Impact factor: 4.158

Review 3. Autophagy, a process within reperfusion injury: an update.

Authors: Bisharad Anil Thapalia; Zhen Zhou; Xianhe Lin
Journal: Int J Clin Exp Pathol Date: 2014-12-01

4. Comparative gene identification-58 (CGI-58) promotes autophagy as a putative lysophosphatidylglycerol acyltransferase.

Authors: Jun Zhang; Dan Xu; Jia Nie; Ruili Han; Yonggong Zhai; Yuguang Shi
Journal: J Biol Chem Date: 2014-10-14 Impact factor: 5.157

5. Adipose-specific knockdown of Sirt1 results in obesity and insulin resistance by promoting exosomes release.

Authors: Fang Li; Huixia Li; Xinxin Jin; Ying Zhang; Xiaomin Kang; Zhuanmin Zhang; Mao Xu; Zhuang Qian; Zhengmin Ma; Xin Gao; Liting Zhao; Shufang Wu; Hongzhi Sun
Journal: Cell Cycle Date: 2019-07-11 Impact factor: 4.534

6. Radiation persistently promoted oxidative stress, activated mTOR via PI3K/Akt, and downregulated autophagy pathway in mouse intestine.

Authors: Kamal Datta; Shubhankar Suman; Albert J Fornace
Journal: Int J Biochem Cell Biol Date: 2014-10-23 Impact factor: 5.085

10. Effect of vitamin D₃ supplementation on hepatic lipid dysregulation associated with autophagy regulatory AMPK/Akt-mTOR signaling in type 2 diabetic mice.

Authors: Hyewon Lim; Heaji Lee; Yunsook Lim
Journal: Exp Biol Med (Maywood) Date: 2021-02-04

Autophagy: a potential link between obesity and insulin resistance.

1. Markers of autophagy are adapted to hyperglycaemia in skeletal muscle in type 2 diabetes.

Review 2. Autophagy regulates insulin resistance following endoplasmic reticulum stress in diabetes.

Review 3. Autophagy, a process within reperfusion injury: an update.

4. Comparative gene identification-58 (CGI-58) promotes autophagy as a putative lysophosphatidylglycerol acyltransferase.

5. Adipose-specific knockdown of Sirt1 results in obesity and insulin resistance by promoting exosomes release.

6. Radiation persistently promoted oxidative stress, activated mTOR via PI3K/Akt, and downregulated autophagy pathway in mouse intestine.

Review 7. Glutamine metabolism in advanced age.

8. Maresin 1 mitigates liver steatosis in ob/ob and diet-induced obese mice.

Review 9. Autophagy modulation as a potential therapeutic target for diverse diseases.

10. Effect of vitamin D₃ supplementation on hepatic lipid dysregulation associated with autophagy regulatory AMPK/Akt-mTOR signaling in type 2 diabetic mice.

Autophagy: a potential link between obesity and insulin resistance.

1. Markers of autophagy are adapted to hyperglycaemia in skeletal muscle in type 2 diabetes.

Review 2. Autophagy regulates insulin resistance following endoplasmic reticulum stress in diabetes.

Review 3. Autophagy, a process within reperfusion injury: an update.

4. Comparative gene identification-58 (CGI-58) promotes autophagy as a putative lysophosphatidylglycerol acyltransferase.

5. Adipose-specific knockdown of Sirt1 results in obesity and insulin resistance by promoting exosomes release.

6. Radiation persistently promoted oxidative stress, activated mTOR via PI3K/Akt, and downregulated autophagy pathway in mouse intestine.

Review 7. Glutamine metabolism in advanced age.

8. Maresin 1 mitigates liver steatosis in ob/ob and diet-induced obese mice.

Review 9. Autophagy modulation as a potential therapeutic target for diverse diseases.

10. Effect of vitamin D3 supplementation on hepatic lipid dysregulation associated with autophagy regulatory AMPK/Akt-mTOR signaling in type 2 diabetic mice.

10. Effect of vitamin D₃ supplementation on hepatic lipid dysregulation associated with autophagy regulatory AMPK/Akt-mTOR signaling in type 2 diabetic mice.