Literature DB >> 20517559

Better shrinkage than Shrinky-Dinks.

Diep Nguyen1, Douglas Taylor, Kun Qian, Nizilla Norouzi, Jerald Rasmussen, Steve Botzet, Matt Lehmann, Kurt Halverson, Michelle Khine.   

Abstract

Polyolefins are finding increased popularity in microfluidic applications due to their attractive mechanical, processing, and optical properties. While intricate features are typically realized in these thermoplastics by hot embossing and injection molding, such fabrication approaches are expensive and slow. Here, we apply our shrink-induced approach-first demonstrated with polystyrene 'Shrinky-Dink' sheets-to create micro- and nanostructures with cross-linked polyolefin thin films. These multi-layered films shrink by 95% and with greater uniformity than the Shrinky-Dinks. With such significant reduction in size, along with attractive material properties, such commodity films could find important applications in low cost microfluidic prototyping as well as in point-of-care diagnostics. In this technical note, we demonstrate the ability to rapidly and easily create unique microstructures, increase microarray feature density, and even induce self-assembled integrated metallic nanostructures with these shrink wrap films.

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Year:  2010        PMID: 20517559     DOI: 10.1039/c001082k

Source DB:  PubMed          Journal:  Lab Chip        ISSN: 1473-0189            Impact factor:   6.799


  13 in total

1.  Shrink-film microfluidic education modules: Complete devices within minutes.

Authors:  Diep Nguyen; Jolie McLane; Valerie Lew; Jonathan Pegan; Michelle Khine
Journal:  Biomicrofluidics       Date:  2011-06-29       Impact factor: 2.800

Review 2.  "Learning on a chip:" Microfluidics for formal and informal science education.

Authors:  Darius G Rackus; Ingmar H Riedel-Kruse; Nicole Pamme
Journal:  Biomicrofluidics       Date:  2019-07-09       Impact factor: 2.800

3.  Shrink-induced sorting using integrated nanoscale magnetic traps.

Authors:  Dharmakeerthi Nawarathna; Nazila Norouzi; Jolie McLane; Himanshu Sharma; Nicholas Sharac; Ted Grant; Aaron Chen; Scott Strayer; Regina Ragan; Michelle Khine
Journal:  Appl Phys Lett       Date:  2013-02-13       Impact factor: 3.791

4.  Separation-encoded microparticles for single-cell western blotting.

Authors:  Burcu Gumuscu; Amy E Herr
Journal:  Lab Chip       Date:  2019-11-27       Impact factor: 6.799

5.  Protein footprinting by pyrite shrink-wrap laminate.

Authors:  Micheal Leser; Jonathan Pegan; Mohammed El Makkaoui; Joerg C Schlatterer; Michelle Khine; Matt Law; Michael Brenowitz
Journal:  Lab Chip       Date:  2015-04-07       Impact factor: 7.517

Review 6.  From cleanroom to desktop: emerging micro-nanofabrication technology for biomedical applications.

Authors:  Tingrui Pan; Wei Wang
Journal:  Ann Biomed Eng       Date:  2010-12-14       Impact factor: 3.934

Review 7.  Unconventional low-cost fabrication and patterning techniques for point of care diagnostics.

Authors:  Himanshu Sharma; Diep Nguyen; Aaron Chen; Valerie Lew; Michelle Khine
Journal:  Ann Biomed Eng       Date:  2010-12-09       Impact factor: 3.934

8.  CheapStat: an open-source, "do-it-yourself" potentiostat for analytical and educational applications.

Authors:  Aaron A Rowe; Andrew J Bonham; Ryan J White; Michael P Zimmer; Ramsin J Yadgar; Tony M Hobza; Jim W Honea; Ilan Ben-Yaacov; Kevin W Plaxco
Journal:  PLoS One       Date:  2011-09-13       Impact factor: 3.240

Review 9.  Thermally-induced miniaturization for micro- and nanofabrication: progress and updates.

Authors:  Sophia Lin; Eugene K Lee; Nancy Nguyen; Michelle Khine
Journal:  Lab Chip       Date:  2014-07-30       Impact factor: 7.517

Review 10.  Increasing the packing density of assays in paper-based microfluidic devices.

Authors:  Sajjad Rahmani Dabbagh; Elaina Becher; Fariba Ghaderinezhad; Hayati Havlucu; Oguzhan Ozcan; Mehmed Ozkan; Ali Kemal Yetisen; Savas Tasoglu
Journal:  Biomicrofluidics       Date:  2021-02-04       Impact factor: 2.800

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