Literature DB >> 20517338

Radiotherapy. Hypofractionation for breast cancer--clinical implications.

Bruce G Haffty1.   

Abstract

A recent landmark study reported the long-term results that compared a standard course of whole-breast irradiation (25 treatments over 5 weeks) with a hypofractionated course of radiation (16 treatments over 3.5 weeks) in patients with early-stage, node-negative breast cancer. The trial demonstrated equivalence of results with respect to overall survival,local control, toxicity and cosmetic outcomes.

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Year:  2010        PMID： 20517338     DOI： 10.1038/nrclinonc.2010.65

Source DB:  PubMed          Journal:  Nat Rev Clin Oncol        ISSN： 1759-4774            Impact factor:   66.675


  10 in total

1.  Effect of radiotherapy fraction size on tumour control in patients with early-stage breast cancer after local tumour excision: long-term results of a randomised trial.

Authors:  J Roger Owen; Anita Ashton; Judith M Bliss; Janis Homewood; Caroline Harper; Jane Hanson; Joanne Haviland; Soren M Bentzen; John R Yarnold
Journal:  Lancet Oncol       Date:  2006-06       Impact factor: 41.316

2.  Long-term results of hypofractionated radiation therapy for breast cancer.

Authors:  Timothy J Whelan; Jean-Philippe Pignol; Mark N Levine; Jim A Julian; Robert MacKenzie; Sameer Parpia; Wendy Shelley; Laval Grimard; Julie Bowen; Himu Lukka; Francisco Perera; Anthony Fyles; Ken Schneider; Sunil Gulavita; Carolyn Freeman
Journal:  N Engl J Med       Date:  2010-02-11       Impact factor: 91.245

3.  Role of a 10-Gy boost in the conservative treatment of early breast cancer: results of a randomized clinical trial in Lyon, France.

Authors:  P Romestaing; Y Lehingue; C Carrie; R Coquard; X Montbarbon; J M Ardiet; N Mamelle; J P Gérard
Journal:  J Clin Oncol       Date:  1997-03       Impact factor: 44.544

4.  Fractionation sensitivity and dose response of late adverse effects in the breast after radiotherapy for early breast cancer: long-term results of a randomised trial.

Authors:  John Yarnold; Anita Ashton; Judith Bliss; Janis Homewood; Caroline Harper; Jane Hanson; Jo Haviland; Søren Bentzen; Roger Owen
Journal:  Radiother Oncol       Date:  2005-03-16       Impact factor: 6.280

Review 5.  Fractionation for whole breast irradiation: an American Society for Radiation Oncology (ASTRO) evidence-based guideline.

Authors:  Benjamin D Smith; Soren M Bentzen; Candace R Correa; Carol A Hahn; Patricia H Hardenbergh; Geoffrey S Ibbott; Beryl McCormick; Julie R McQueen; Lori J Pierce; Simon N Powell; Abram Recht; Alphonse G Taghian; Frank A Vicini; Julia R White; Bruce G Haffty
Journal:  Int J Radiat Oncol Biol Phys       Date:  2010-07-16       Impact factor: 7.038

6.  Randomized trial of breast irradiation schedules after lumpectomy for women with lymph node-negative breast cancer.

Authors:  Timothy Whelan; Robert MacKenzie; Jim Julian; Mark Levine; Wendy Shelley; Laval Grimard; Barbara Lada; Himu Lukka; Francisco Perera; Anthony Fyles; Ethan Laukkanen; Sunil Gulavita; Veronique Benk; Barbara Szechtman
Journal:  J Natl Cancer Inst       Date:  2002-08-07       Impact factor: 13.506

7.  Impact of a higher radiation dose on local control and survival in breast-conserving therapy of early breast cancer: 10-year results of the randomized boost versus no boost EORTC 22881-10882 trial.

Authors:  Harry Bartelink; Jean-Claude Horiot; Philip M Poortmans; Henk Struikmans; Walter Van den Bogaert; Alain Fourquet; Jos J Jager; Willem J Hoogenraad; S Bing Oei; Carla C Wárlám-Rodenhuis; Marianne Pierart; Laurence Collette
Journal:  J Clin Oncol       Date:  2007-06-18       Impact factor: 44.544

8.  Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer.

Authors:  Bernard Fisher; Stewart Anderson; John Bryant; Richard G Margolese; Melvin Deutsch; Edwin R Fisher; Jong-Hyeon Jeong; Norman Wolmark
Journal:  N Engl J Med       Date:  2002-10-17       Impact factor: 91.245

9.  Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer.

Authors:  Umberto Veronesi; Natale Cascinelli; Luigi Mariani; Marco Greco; Roberto Saccozzi; Alberto Luini; Marisel Aguilar; Ettore Marubini
Journal:  N Engl J Med       Date:  2002-10-17       Impact factor: 91.245

10.  The UK Standardisation of Breast Radiotherapy (START) Trial B of radiotherapy hypofractionation for treatment of early breast cancer: a randomised trial.

Authors:  S M Bentzen; R K Agrawal; E G A Aird; J M Barrett; P J Barrett-Lee; S M Bentzen; J M Bliss; J Brown; J A Dewar; H J Dobbs; J S Haviland; P J Hoskin; P Hopwood; P A Lawton; B J Magee; J Mills; D A L Morgan; J R Owen; S Simmons; G Sumo; M A Sydenham; K Venables; J R Yarnold
Journal:  Lancet       Date:  2008-03-19       Impact factor: 79.321
  10 in total

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