Literature DB >> 20514051

IL-17 signaling in host defense and inflammatory diseases.

Youcun Qian1, Zizhen Kang, Caini Liu, Xiaoxia Li.   

Abstract

Interleukin (IL)-17, the signature cytokine secreted by T helper (Th) 17 cells, plays important roles in host defense against extracellular bacterial infection and fungal infection and contributes to the pathogenesis of various autoimmune inflammatory diseases. Here we review the recent advances in IL-17-mediated functions with emphasis on the studies of IL-17-mediated signal transduction, providing perspective on potential drug targets for the treatment of autoimmune inflammatory diseases.

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Year:  2010        PMID： 20514051      PMCID： PMC4002676          DOI： 10.1038/cmi.2010.27

Source DB:  PubMed          Journal:  Cell Mol Immunol        ISSN： 1672-7681            Impact factor:   11.530


  70 in total

Review 1.  IL-17 family cytokines and the expanding diversity of effector T cell lineages.

Authors:  Casey T Weaver; Robin D Hatton; Paul R Mangan; Laurie E Harrington
Journal:  Annu Rev Immunol       Date:  2007       Impact factor: 28.527

2.  An essential role for IL-17 in preventing pathogen-initiated bone destruction: recruitment of neutrophils to inflamed bone requires IL-17 receptor-dependent signals.

Authors:  Jeffrey J Yu; Matthew J Ruddy; Grace C Wong; Cornelia Sfintescu; Pamela J Baker; Jeffrey B Smith; Richard T Evans; Sarah L Gaffen
Journal:  Blood       Date:  2007-01-03       Impact factor: 22.113

3.  The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease.

Authors:  Youcun Qian; Caini Liu; Justin Hartupee; Cengiz Zubeyir Altuntas; Muhammet Fatih Gulen; Daniel Jane-Wit; Jianhua Xiao; Yi Lu; Natalia Giltiay; Jinbo Liu; Tomasz Kordula; Qi-Wei Zhang; Bruce Vallance; Shadi Swaidani; Mark Aronica; Vincent K Tuohy; Thomas Hamilton; Xiaoxia Li
Journal:  Nat Immunol       Date:  2007-02-04       Impact factor: 25.606

4.  IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis.

Authors:  Yutaka Komiyama; Susumu Nakae; Taizo Matsuki; Aya Nambu; Harumichi Ishigame; Shigeru Kakuta; Katsuko Sudo; Yoichiro Iwakura
Journal:  J Immunol       Date:  2006-07-01       Impact factor: 5.422

5.  Act1 adaptor protein is an immediate and essential signaling component of interleukin-17 receptor.

Authors:  Seon Hee Chang; Heon Park; Chen Dong
Journal:  J Biol Chem       Date:  2006-10-11       Impact factor: 5.157

6.  Identification and functional characterization of a novel interleukin 17 receptor: a possible mitogenic activation through ras/mitogen-activated protein kinase signaling pathway.

Authors:  Tie-Shi Li; Xue-Ni Li; Zhi-Jie Chang; Xin-Yuan Fu; Li Liu
Journal:  Cell Signal       Date:  2005-11-28       Impact factor: 4.315

7.  Requirement for both JAK-mediated PI3K signaling and ACT1/TRAF6/TAK1-dependent NF-kappaB activation by IL-17A in enhancing cytokine expression in human airway epithelial cells.

Authors:  Fei Huang; Cheng-Yuan Kao; Shinichiro Wachi; Philip Thai; Jisu Ryu; Reen Wu
Journal:  J Immunol       Date:  2007-11-15       Impact factor: 5.422

8.  Interleukin-17A modulates human airway epithelial responses to human rhinovirus infection.

Authors:  Shahina Wiehler; David Proud
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2007-06-01       Impact factor: 5.464

9.  IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC-activated Th2 memory cells.

Authors:  Yui-Hsi Wang; Pornpimon Angkasekwinai; Ning Lu; Kui Shin Voo; Kazuhiko Arima; Shino Hanabuchi; Andreas Hippe; Chris J Corrigan; Chen Dong; Bernhard Homey; Zhengbin Yao; Sun Ying; David P Huston; Yong-Jun Liu
Journal:  J Exp Med       Date:  2007-07-16       Impact factor: 14.307

10.  Interleukin 25 promotes the initiation of proallergic type 2 responses.

Authors:  Pornpimon Angkasekwinai; Heon Park; Yui-Hsi Wang; Yi-Hong Wang; Seon Hee Chang; David B Corry; Yong-Jun Liu; Zhou Zhu; Chen Dong
Journal:  J Exp Med       Date:  2007-06-11       Impact factor: 14.307
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  33 in total

1.  The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α.

Authors:  Shu Zhu; Wen Pan; Xinyang Song; Yan Liu; Xinrui Shao; Yuanjia Tang; Dong Liang; Dongyi He; Honglin Wang; Wenjun Liu; Yufang Shi; John B Harley; Nan Shen; Youcun Qian
Journal:  Nat Med       Date:  2012-07       Impact factor: 53.440

2.  Polyclonal mucosa-associated invariant T cells have unique innate functions in bacterial infection.

Authors:  Wei-Jen Chua; Steven M Truscott; Christopher S Eickhoff; Azra Blazevic; Daniel F Hoft; Ted H Hansen
Journal:  Infect Immun       Date:  2012-07-09       Impact factor: 3.441

3.  Genetic polymorphisms of interleukin 17A and interleukin 17F and their association with inflammatory bowel disease in a Chinese Han population.

Authors:  Xiaofei Zhang; Pengli Yu; Ying Wang; Wenyu Jiang; Fangcheng Shen; Yamin Wang; Huiming Tu; Xiaozhong Yang; Ruihua Shi; Hongjie Zhang
Journal:  Inflamm Res       Date:  2013-05-08       Impact factor: 4.575

4.  Interleukin-17A stimulates cardiac fibroblast proliferation and migration via negative regulation of the dual-specificity phosphatase MKP-1/DUSP-1.

Authors:  Anthony J Valente; Tadashi Yoshida; Jason D Gardner; Naveen Somanna; Patrice Delafontaine; Bysani Chandrasekar
Journal:  Cell Signal       Date:  2011-10-20       Impact factor: 4.315

5.  Plasma CXCL1 levels and TRAF3IP2 variants in patients with myocardial infarction.

Authors:  Safoora Pordel; Mahdi Sajedi Khanian; Mohammad Hossein Karimi; Hossein Nikoo; Mehrnoosh Doroudchi
Journal:  J Clin Lab Anal       Date:  2018-02-12       Impact factor: 2.352

6.  Targeting Th17-IL-17 Pathway in Prevention of Micro-Invasive Prostate Cancer in a Mouse Model.

Authors:  Qiuyang Zhang; Sen Liu; Dongxia Ge; David M Cunningham; Feng Huang; Lin Ma; Thomas P Burris; Zongbing You
Journal:  Prostate       Date:  2017-02-27       Impact factor: 4.104

7.  Treatment with the interleukin-17A-blocking antibody secukinumab does not interfere with the efficacy of influenza and meningococcal vaccinations in healthy subjects: results of an open-label, parallel-group, randomized single-center study.

Authors:  A Chioato; E Noseda; M Stevens; N Gaitatzis; A Kleinschmidt; H Picaud
Journal:  Clin Vaccine Immunol       Date:  2012-08-08

8.  A knowledgebase resource for interleukin-17 family mediated signaling.

Authors:  Jyoti Sharma; Lavanya Balakrishnan; Keshava K Datta; Nandini A Sahasrabuddhe; Aafaque Ahmad Khan; Apeksha Sahu; Anish Singhal; Derese Getnet; Rajesh Raju; Aditi Chatterjee; Harsha Gowda; T S Keshava Prasad; Subramanian Shankar; Akhilesh Pandey
Journal:  J Cell Commun Signal       Date:  2015-06-16       Impact factor: 5.782

9.  The glutaredoxin/S-glutathionylation axis regulates interleukin-17A-induced proinflammatory responses in lung epithelial cells in association with S-glutathionylation of nuclear factor κB family proteins.

Authors:  James D Nolin; Jane E Tully; Sidra M Hoffman; Amy S Guala; Jos L van der Velden; Matthew E Poynter; Albert van der Vliet; Vikas Anathy; Yvonne M W Janssen-Heininger
Journal:  Free Radic Biol Med       Date:  2014-05-09       Impact factor: 7.376

10.  Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling.

Authors:  Shu Zhu; Wen Pan; Peiqing Shi; Hanchao Gao; Fang Zhao; Xinyang Song; Yan Liu; Lihua Zhao; Xiaoxia Li; Yufang Shi; Youcun Qian
Journal:  J Exp Med       Date:  2010-11-15       Impact factor: 14.307
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