| Literature DB >> 20513552 |
Abstract
Prion diseases are disorders affecting the central nervous system caused by alterations in the conformation of the cellular prion protein. They can be sporadic, hereditary, or acquired and usually present with myoclonus and rapidly progressive dementia in human patients. This article discusses the epidemiology, pathogenesis, diagnosis, and laboratory testing of prion diseases with a primary focus on Creutzfeldt-Jakob disease. 2010 Elsevier Inc. All rights reserved.Entities:
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Year: 2010 PMID： 20513552 DOI： 10.1016/j.cll.2009.11.002
Source DB: PubMed Journal: Clin Lab Med ISSN： 0272-2712 Impact factor: 1.935