Literature DB >> 20512552

Proton magnetic resonance spectroscopy findings of hemangioblastoma.

Tomonori Isobe1, Tetsuya Yamamoto, Hiroyoshi Akutsu, Izumi Anno, Masanari Shiigai, Alexander Zaboronok, Tomohiko Masumoto, Shingo Takano, Akira Matsumura.   

Abstract

We report a case of proton magnetic resonance spectroscopy (MRS) of hemangioblastoma in a 56-yearold man with a history of hyperlipidemia who was suffering from an equilibrium disorder. Proton MRS revealed a high mobile lipids (Lip) peak between 0.9 and 1.4 ppm, which was compatible with histologically proven lipids in the tumor. No lactate peak was recognized. The creatine/phosphocreatine peak was low. Choline-containing compounds were increased. The N-acetylaspartate peak was absent, which indicated that the tumor is of nonneurogenic origin. Combined with the absence of the necrotic component on magnetic resonance imaging, this Lip peak on proton MRS could be the characteristic pattern of hemangioblastoma. These unique results of proton MRS can play an important role in the differential diagnosis of intracranial hemangioblastoma. However, further investigations are required to establish the typical characteristics of proton MRS of hemangioblastoma.

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Year:  2010        PMID: 20512552     DOI: 10.1007/s11604-010-0421-5

Source DB:  PubMed          Journal:  Jpn J Radiol        ISSN: 1867-1071            Impact factor:   2.374


  10 in total

1.  Localized high-resolution proton NMR spectroscopy using stimulated echoes: initial applications to human brain in vivo.

Authors:  J Frahm; H Bruhn; M L Gyngell; K D Merboldt; W Hänicke; R Sauter
Journal:  Magn Reson Med       Date:  1989-01       Impact factor: 4.668

2.  Proton magnetic resonance spectroscopy and intracranial tumours: clinical perspectives.

Authors:  A Falini; G Calabrese; D Origgi; S Lipari; F Triulzi; M Losa; G Scotti
Journal:  J Neurol       Date:  1996-10       Impact factor: 4.849

3.  Effect of J coupling and T2 Relaxation in Assessing of Methyl Lactate Signal using PRESS Sequence MR Spectroscopy.

Authors:  Tomonori Isobe; Akira Matsumura; Izumi Anno; Hiraku Kawamura; Hiroshi Muraishi; Tokuo Umeda; Tadao Nose
Journal:  Igaku Butsuri       Date:  2005

4.  von Hippel-Lindau gene deletion detected in the stromal cell component of a cerebellar hemangioblastoma associated with von Hippel-Lindau disease.

Authors:  A O Vortmeyer; J R Gnarra; M R Emmert-Buck; D Katz; W M Linehan; E H Oldfield; Z Zhuang
Journal:  Hum Pathol       Date:  1997-05       Impact factor: 3.466

5.  Cerebellar hemangioblastoma simulating arachnoid cyst on imaging and surgery.

Authors:  D K Vatsal; M Husain; N Husain; S Chawla; R Roy; Rakesh K Gupta
Journal:  Neurosurg Rev       Date:  2002-03       Impact factor: 3.042

6.  (1)H-MRS metabolic patterns for distinguishing between meningiomas and other brain tumors.

Authors:  Young-Dae Cho; Gi-Hwan Choi; Sang-Pyung Lee; Jong-Ki Kim
Journal:  Magn Reson Imaging       Date:  2003-07       Impact factor: 2.546

Review 7.  A review of chemical issues in 1H NMR spectroscopy: N-acetyl-L-aspartate, creatine and choline.

Authors:  B L Miller
Journal:  NMR Biomed       Date:  1991-04       Impact factor: 4.044

Review 8.  Ultrastructure of cerebellar hemangioblastoma.

Authors:  A P Chaudhry; M Montes; G A Cohn
Journal:  Cancer       Date:  1978-10       Impact factor: 6.860

Review 9.  What the clinician can learn from MRS lactate measurements.

Authors:  J W Prichard
Journal:  NMR Biomed       Date:  1991-04       Impact factor: 4.044

10.  Lipid signal in evaluation of intracranial meningiomas.

Authors:  Zhi-gang Qi; Yu-xin Li; Yan Wang; Dao-yin Geng; Kun-cheng Li; Tian-zhen Shen; Xin-rong Chen
Journal:  Chin Med J (Engl)       Date:  2008-12-05       Impact factor: 2.628

  10 in total
  5 in total

1.  Differentiation of hemangioblastomas from pilocytic astrocytomas using 3-T magnetic resonance perfusion-weighted imaging and MR spectroscopy.

Authors:  D J She; Z Xing; Z Zeng; X Y Shang; D R Cao
Journal:  Neuroradiology       Date:  2014-12-07       Impact factor: 2.804

2.  Midline basifrontal solid hemangioblastoma in non von hippel lindau syndrome patient.

Authors:  Avijit Sarkari; Deepak Agrawal
Journal:  J Neurosci Rural Pract       Date:  2012-09

3.  Intensity-Curvature Measurement Approaches for the Diagnosis of Magnetic Resonance Imaging Brain Tumors.

Authors:  Carlo Ciulla; Dimitar Veljanovski; Ustijana Rechkoska Shikoska; Filip A Risteski
Journal:  J Adv Res       Date:  2015-01-09       Impact factor: 10.479

Review 4.  Supratentorial haemangioblastoma without von Hippel-Lindau syndrome in an adult: A rare tumor with review of literature.

Authors:  Sharad Pandey; Vivek Sharma; Deepa Pandey; Vikul Kumar; Mohan Kumar
Journal:  Asian J Neurosurg       Date:  2016 Jan-Mar

5.  Advanced magnetic resonance imaging findings of cerebellar hemangioblastomas: A report of three cases and a literature review.

Authors:  Eiji Matsusue; Chie Inoue; Sadaharu Tabuchi; Hiroki Yoshioka; Yuichiro Nagao; Kensuke Matsumoto; Kazuhiko Nakamura; Shinya Fujii
Journal:  Acta Radiol Open       Date:  2022-03-03
  5 in total

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