PURPOSE: The aim of this study was to evaluate the accuracy of dynamic gadolinium (Gd)-enhanced magnetic resonance imaging (MRI) with endorectal coil for assessing tumor invasion based on simple classification criteria. MATERIALS AND METHODS: A total of 58 patients with operable primary rectal cancer underwent preoperative MRI. An enhancement pattern in Gd-enhanced dynamic MRI with regard to tumor penetration was clarified. Retrospectively, two observers independently scored T2-weighted MRI and T2-weighted MRI combined with Gd-enhanced dynamic MRI for tumor penetration using the following criteria: With Gd-enhanced dynamic MRI, T1 tumors showed an early enhanced line around the tumor as rim enhancement; T2 tumors appeared as black lines or double layers, as the muscularis propria kept its integrity; T3 tumors showed partial discontinuity of the muscularis propria as a dotted line and a perforated area as an interrupted line. A confidence level scoring system was used, and receiver operating characteristic curves were generated. RESULTS: There were no significant differences at the T1 stage. There were significant differences for observer 1 (P = 0.001 for observer 1) at the T2 stage. There were significant differences for both observers (P = 0.001 for observer 1 and P = 0.005 for observer 2) at the T3 stage. CONCLUSION: Our criteria for Gd-enhanced dynamic MRI were effective for T3 stage tumors.
PURPOSE: The aim of this study was to evaluate the accuracy of dynamic gadolinium (Gd)-enhanced magnetic resonance imaging (MRI) with endorectal coil for assessing tumor invasion based on simple classification criteria. MATERIALS AND METHODS: A total of 58 patients with operable primary rectal cancer underwent preoperative MRI. An enhancement pattern in Gd-enhanced dynamic MRI with regard to tumor penetration was clarified. Retrospectively, two observers independently scored T2-weighted MRI and T2-weighted MRI combined with Gd-enhanced dynamic MRI for tumor penetration using the following criteria: With Gd-enhanced dynamic MRI, T1 tumors showed an early enhanced line around the tumor as rim enhancement; T2 tumors appeared as black lines or double layers, as the muscularis propria kept its integrity; T3 tumors showed partial discontinuity of the muscularis propria as a dotted line and a perforated area as an interrupted line. A confidence level scoring system was used, and receiver operating characteristic curves were generated. RESULTS: There were no significant differences at the T1 stage. There were significant differences for observer 1 (P = 0.001 for observer 1) at the T2 stage. There were significant differences for both observers (P = 0.001 for observer 1 and P = 0.005 for observer 2) at the T3 stage. CONCLUSION: Our criteria for Gd-enhanced dynamic MRI were effective for T3 stage tumors.
Authors: C G Hodgman; R L MacCarty; B G Wolff; G R May; T H Berquist; P F Sheedy; R W Beart; R J Spencer Journal: Dis Colon Rectum Date: 1986-07 Impact factor: 4.585
Authors: R J Zagoria; C A Schlarb; D J Ott; R I Bechtold; N T Wolfman; E S Scharling; M Y Chen; B W Loggie Journal: J Surg Oncol Date: 1997-04 Impact factor: 3.454
Authors: Roy F A Vliegen; Geerard L Beets; Maarten F von Meyenfeldt; Alfons G H Kessels; Etienne E M T Lemaire; Jos M A van Engelshoven; Regina G H Beets-Tan Journal: Radiology Date: 2004-11-18 Impact factor: 11.105