Literature DB >> 20511737

Use of lamotrigine in a patient with a clozapine-related seizure.

Andrew Muzyk1, Gary Gala, David A Kahn.   

Abstract

Seizures can be a serious adverse effect of clozapine, often a last-resort antipsychotic with unique efficacy for some patients. Several anticonvulsants have been reported to be useful in preventing further clozapine-induced seizures and permitting continued treatment with this medication. The authors describe the first reported successful use of lamotrigine for this purpose.

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Year:  2010        PMID: 20511737     DOI: 10.1097/01.pra.0000369974.18274.e2

Source DB:  PubMed          Journal:  J Psychiatr Pract        ISSN: 1527-4160            Impact factor:   1.325


  4 in total

Review 1.  Seizure associated with clozapine: incidence, etiology, and management.

Authors:  Andrew M Williams; Susie H Park
Journal:  CNS Drugs       Date:  2015-02       Impact factor: 5.749

2.  Japanese Society of Neuropsychopharmacology: "Guideline for Pharmacological Therapy of Schizophrenia".

Authors: 
Journal:  Neuropsychopharmacol Rep       Date:  2021-08-12

3.  Clozapine-related EEG changes and seizures: dose and plasma-level relationships.

Authors:  Seema Varma; Delia Bishara; Frank M C Besag; David Taylor
Journal:  Ther Adv Psychopharmacol       Date:  2011-04

4.  Low-dose clozapine-related seizure: A case report and literature review.

Authors:  Dan-Sheng Le; Heng Su; Zheng-Luan Liao; En-Yan Yu
Journal:  World J Clin Cases       Date:  2021-07-16       Impact factor: 1.337

  4 in total

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