What are the minimal standards of radiotherapy planning and dosimetry for "hypofractionated" radiotherapy in breast cancer?

Hypofractionated radiotherapy regimens have become increasingly popular in breast cancer, particularly in the UK and Canada. However, there are some potential problems inherent to providing such regimens, such as the concern of increased toxicity. In this article we discuss the planning and dosimetry and requirements for hypofractionated radiotherapy in breast cancer and make recommendations both for the planning process and for treatment monitoring. Copyright (c) 2010 Elsevier Ltd. All rights reserved.