| Literature DB >> 20510766 |
Meng Chen1, Sean D Doherty, Sylvia Hsu.
Abstract
Thalidomide is approved for treating erythema nodosum leprosum and multiple myeloma, but it has also emerged as a useful treatment option for many refractory dermatologic disorders. Some of the innovative but off-label uses of thalidomide include aphthous stomatitis, Behçet's disease, lupus erythematosus, prurigo nodularis, sarcoidosis, actinic prurigo, graft-versus-host disease, Langerhans cell histiocytosis, erythema multiforme, lichen planus, Kaposi sarcoma, Jessner lymphocytic infiltrate, uremic pruritus, pyoderma gangrenosum, scleroderma, scleromyxedema, and necrobiosis lipoidica. This article reviews the background, pharmacology, and innovative uses of thalidomide in dermatology. Copyright 2010 Elsevier Inc. All rights reserved.Entities:
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Year: 2010 PMID： 20510766 DOI： 10.1016/j.det.2010.03.003
Source DB: PubMed Journal: Dermatol Clin ISSN： 0733-8635 Impact factor: 3.478