Literature DB >> 20508615

Physiological hypoxia promotes lipid raft and PI3K-dependent activation of MAPK 42/44 in leukemia cells.

M Fiegl, I Samudio, Z Mnjoyan, B Korchin, H Fritsche, M Andreeff.   

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Year:  2010        PMID： 20508615      PMCID： PMC4105972          DOI： 10.1038/leu.2010.94

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


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  10 in total

1.  Oxygen saturation in the bone marrow of healthy volunteers.

Authors:  Jonathan S Harrison; Pranela Rameshwar; Vicotr Chang; Persis Bandari
Journal:  Blood       Date:  2002-01-01       Impact factor: 22.113

2.  Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia.

Authors:  Kalindi Parmar; Peter Mauch; Jo-Anne Vergilio; Robert Sackstein; Julian D Down
Journal:  Proc Natl Acad Sci U S A       Date:  2007-03-20       Impact factor: 11.205

Review 3.  Uncertainty in the niches that maintain haematopoietic stem cells.

Authors:  Mark J Kiel; Sean J Morrison
Journal:  Nat Rev Immunol       Date:  2008-03-07       Impact factor: 53.106

4.  Phase I/II study of combination therapy with sorafenib, idarubicin, and cytarabine in younger patients with acute myeloid leukemia.

Authors:  Farhad Ravandi; Jorge E Cortes; Daniel Jones; Stefan Faderl; Guillermo Garcia-Manero; Marina Y Konopleva; Susan O'Brien; Zeev Estrov; Gautam Borthakur; Deborah Thomas; Sherry R Pierce; Mark Brandt; Anna Byrd; B Nebiyou Bekele; Keith Pratz; Rajyalakshmi Luthra; Mark Levis; Michael Andreeff; Hagop M Kantarjian
Journal:  J Clin Oncol       Date:  2010-03-08       Impact factor: 44.544

5.  The role of hypoxia in the maintenance of hematopoietic stem cells.

Authors:  M G Cipolleschi; P Dello Sbarba; M Olivotto
Journal:  Blood       Date:  1993-10-01       Impact factor: 22.113

6.  Activation of mitogen-activated protein kinase by membrane-targeted Raf chimeras is independent of raft localization.

Authors:  X Chen; M D Resh
Journal:  J Biol Chem       Date:  2001-07-16       Impact factor: 5.157

7.  Constitutive activation of mitogen-activated protein kinase pathway in acute leukemia cells.

Authors:  M Towatari; H Iida; M Tanimoto; H Iwata; M Hamaguchi; H Saito
Journal:  Leukemia       Date:  1997-04       Impact factor: 11.528

8.  CXCR4 expression and biologic activity in acute myeloid leukemia are dependent on oxygen partial pressure.

Authors:  Michael Fiegl; Ismael Samudio; Karen Clise-Dwyer; Jared K Burks; Zakar Mnjoyan; Michael Andreeff
Journal:  Blood       Date:  2008-10-28       Impact factor: 22.113

9.  Functional proteomic profiling of AML predicts response and survival.

Authors:  Steven M Kornblau; Raoul Tibes; Yi Hua Qiu; Wenjing Chen; Hagop M Kantarjian; Michael Andreeff; Kevin R Coombes; Gordon B Mills
Journal:  Blood       Date:  2008-10-07       Impact factor: 22.113

10.  Modulation of phosphoinositide 3-kinase activation by cholesterol level suggests a novel positive role for lipid rafts in lysophosphatidic acid signalling.

Authors:  Christine Peres; Armelle Yart; Bertrand Perret; Jean Pierre Salles; Patrick Raynal
Journal:  FEBS Lett       Date:  2003-01-16       Impact factor: 4.124
  10 in total
  9 in total

1.  Mechanisms of apoptosis induction by simultaneous inhibition of PI3K and FLT3-ITD in AML cells in the hypoxic bone marrow microenvironment.

Authors:  Linhua Jin; Yoko Tabe; Hongbo Lu; Gautam Borthakur; Takashi Miida; Hagop Kantarjian; Michael Andreeff; Marina Konopleva
Journal:  Cancer Lett       Date:  2012-10-02       Impact factor: 8.679

2.  Therapeutic sensitivity to Rac GTPase inhibition requires consequential suppression of mTORC1, AKT, and MEK signaling in breast cancer.

Authors:  Riley A Hampsch; Kevin Shee; Darcy Bates; Lionel D Lewis; Laurent Désiré; Bertrand Leblond; Eugene Demidenko; Kurtis Stefan; Yina H Huang; Todd W Miller
Journal:  Oncotarget       Date:  2017-03-28

Review 3.  Exosomes in the hypoxic TME: from release, uptake and biofunctions to clinical applications.

Authors:  Guangpeng He; Xueqiang Peng; Shibo Wei; Shuo Yang; Xinyu Li; Mingyao Huang; Shilei Tang; Hongyuan Jin; Jiaxing Liu; Sheng Zhang; Hongyu Zheng; Qing Fan; Jingang Liu; Liang Yang; Hangyu Li
Journal:  Mol Cancer       Date:  2022-01-17       Impact factor: 27.401

4.  Activation of ERK-Drp1 signaling promotes hypoxia-induced Aβ accumulation by upregulating mitochondrial fission and BACE1 activity.

Authors:  Yuan Yuan; Jingjiong Chen; Xuhua Ge; Jiangshan Deng; Xiaofeng Xu; Yuwu Zhao; Hongmei Wang
Journal:  FEBS Open Bio       Date:  2021-08-27       Impact factor: 2.693

5.  IL-8 as mediator in the microenvironment-leukaemia network in acute myeloid leukaemia.

Authors:  Alexander Kuett; Christina Rieger; Deborah Perathoner; Tobias Herold; Michaela Wagner; Silvia Sironi; Karl Sotlar; Hans-Peter Horny; Christian Deniffel; Heidrun Drolle; Michael Fiegl
Journal:  Sci Rep       Date:  2015-12-17       Impact factor: 4.379

6.  Microenvironmental hypoxia regulates FLT3 expression and biology in AML.

Authors:  Silvia Sironi; Michaela Wagner; Alexander Kuett; Heidrun Drolle; Harald Polzer; Karsten Spiekermann; Christina Rieger; Michael Fiegl
Journal:  Sci Rep       Date:  2015-11-30       Impact factor: 4.379

7.  CD45 phosphatase is crucial for human and murine acute myeloid leukemia maintenance through its localization in lipid rafts.

Authors:  Laetitia Saint-Paul; Chi-Hung Nguyen; Anne Buffière; Jean-Paul Pais de Barros; Arlette Hammann; Corinne Landras-Guetta; Rodolphe Filomenko; Marie-Lorraine Chrétien; Pauline Johnson; Jean-Noël Bastie; Laurent Delva; Ronan Quéré
Journal:  Oncotarget       Date:  2016-10-04

8.  The arginase inhibitor Nω-hydroxy-nor-arginine (nor-NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as the functional target.

Authors:  King Pan Ng; Aditi Manjeri; Lin Ming Lee; Zhu En Chan; Chin Yee Tan; Qiancheng Darren Tan; A'Qilah Majeed; Kian Leong Lee; Charles Chuah; Toshio Suda; S Tiong Ong
Journal:  PLoS One       Date:  2018-10-11       Impact factor: 3.240

Review 9.  Leukemia stem cell-bone marrow microenvironment interplay in acute myeloid leukemia development.

Authors:  Yiyi Yao; Fenglin Li; Jiansong Huang; Jie Jin; Huafeng Wang
Journal:  Exp Hematol Oncol       Date:  2021-07-10
  9 in total

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