Literature DB >> 20506884

The treatment of radial scars in the modern era--surgical excision is not required.

Vance Y Sohn1, Marlin W Causey, Scott R Steele, Joren B Keylock, Tommy A Brown.   

Abstract

The clinical significance of isolated radial scars (RS) diagnosed on core needle biopsy (CNB) remains unclear. By determining the pathologic concordance rate, we sought to define the indications for surgical excision for RS diagnosed on CNB. Between January 1994 and December 2007, 38 RS were diagnosed by CNB. Twenty-eight underwent surgical excision with 27 (96%) patients having further benign diagnoses. One patient, who was found to have invasive cancer on CNB, was also found to have malignancy on open biopsy. Fourteen lesions were diagnosed by 8-gauge, 13 lesions by 11-gauge, and one lesion by 14-gauge biopsy needles. Seven studies met inclusion criteria for analysis; 341 lesions with follow-on surgical biopsy were identified. Sixteen (5%) radial'scars were found to harbor malignancy and all were percutaneously biopsied with 14-gauge needles. With the inclusion of the current study, none of the isolated radial scars diagnosed by the larger 11- or 8-gauge biopsy needles resulted in upgraded lesions on follow-on surgical biopsy. Based on the current review, histologic radial scars are infrequently associated with occult malignancy and do not mandate surgical excision. Indications for excision include the mammographic diagnosis of RS and specimens associated with atypia that would otherwise require open biopsy.

Entities:  

Mesh:

Year:  2010        PMID: 20506884

Source DB:  PubMed          Journal:  Am Surg        ISSN: 0003-1348            Impact factor:   0.688


  6 in total

1.  Radial Scar at Image-guided Needle Biopsy: Is Excision Necessary?

Authors:  Niamh Conlon; Clare D'Arcy; Jennifer B Kaplan; Zenica L Bowser; Anibal Cordero; Edi Brogi; Adriana D Corben
Journal:  Am J Surg Pathol       Date:  2015-06       Impact factor: 6.394

2.  Radial scar/complex sclerosing lesions: a clinicopathologic correlation study from a single institution.

Authors:  Aziza Nassar; Amy L Conners; Betul Celik; Sarah M Jenkins; Carin Y Smith; Tina J Hieken
Journal:  Ann Diagn Pathol       Date:  2014-12-20       Impact factor: 2.090

3.  Malignancy Upgrade Rates of Radial Sclerosing Lesions at Breast Cancer Screening.

Authors:  Pamela Yan; Linda DeMello; Grayson L Baird; Ana P Lourenco
Journal:  Radiol Imaging Cancer       Date:  2021-11

4.  Radial scar on image-guided breast biopsy: is surgical excision necessary?

Authors:  Wendy Yen Yun Chou; Deborah J Veis; Rebecca Aft
Journal:  Breast Cancer Res Treat       Date:  2018-03-12       Impact factor: 4.872

5.  Radial scars/complex sclerosing lesions of the breast: radiologic and clinicopathologic correlation.

Authors:  Su Min Ha; Joo Hee Cha; Hee Jung Shin; Eun Young Chae; Woo Jung Choi; Hak Hee Kim; Ha-Yeon Oh
Journal:  BMC Med Imaging       Date:  2018-11-03       Impact factor: 1.930

6.  Isolated radial scar diagnosis by core-needle biopsy: Is surgical excision necessary?

Authors:  Elizabeth Min Hui Kim; Andrea Hankins; Jamie Cassity; Dennis McDonald; Barbara White; Ron Rowberry; Sharon Dutton; Claire Snyder
Journal:  Springerplus       Date:  2016-03-31
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.