Literature DB >> 20505921

[Insomnia in the elderly. An under-diagnosed and over-treated syndrome].

S Schwarz1, L Frölich, M Deuschle.   

Abstract

In elderly patients, insomnia is a common symptom. Insomnia exerts immediate negative effects on quality of life, but also shows a strong bidirectional relationship with serious medical problems. The complex etiology of insomnia in elderly persons warrants meticulous diagnostic assessment. In patients with secondary insomnia, therapy of the causative factors is initiated. Non-pharmacological therapies and behavioral advice constitute the mainstay of symptomatic treatment of insomnia. However, in elderly persons, the efficacy of these measures has not been well established. In general, the therapeutic benefit of hypnotic drugs is small. On the other hand, most substances may have considerable negative side effects. For short-term symptomatic treatment of acute insomnia, hypnotic drugs may be employed. For this indication, Benzodiazepine receptor agonists and prolonged-release Melatonin are drugs of first choice. Generally, prolonged treatment of chronic insomnia in elderly patients is not indicated due to the unclear long-term efficacy and negative side effects of the hypnotic drugs currently available.

Entities:  

Mesh:

Year:  2010        PMID: 20505921     DOI: 10.1007/s00108-010-2647-9

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN: 0020-9554            Impact factor:   0.743


  45 in total

Review 1.  Prescription drug misuse/abuse in the elderly.

Authors:  John W Culberson; Martin Ziska
Journal:  Geriatrics       Date:  2008-09-01

Review 2.  Prolonged-release melatonin for the treatment of insomnia in patients over 55 years.

Authors:  Alan Wade; Susan Downie
Journal:  Expert Opin Investig Drugs       Date:  2008-10       Impact factor: 6.206

Review 3.  Homeopathy for insomnia: a systematic review of research evidence.

Authors:  Katy L Cooper; Clare Relton
Journal:  Sleep Med Rev       Date:  2010-03-11       Impact factor: 11.609

4.  Prevalence of insomnia and its associated factors in elderly long-term care residents.

Authors:  Philippe Voyer; René Verreault; Pamphile Nkogho Mengue; Charles M Morin
Journal:  Arch Gerontol Geriatr       Date:  2005-08-25       Impact factor: 3.250

Review 5.  Comparative efficacy of newer hypnotic drugs for the short-term management of insomnia: a systematic review and meta-analysis.

Authors:  Yenal Dündar; Susanna Dodd; Judith Strobl; Angela Boland; Rumona Dickson; Tom Walley
Journal:  Hum Psychopharmacol       Date:  2004-07       Impact factor: 1.672

6.  A multicenter, placebo-controlled trial of melatonin for sleep disturbance in Alzheimer's disease.

Authors:  Clifford Singer; Rochelle E Tractenberg; Jeffrey Kaye; Kim Schafer; Anthony Gamst; Michael Grundman; Ronald Thomas; Leon J Thal
Journal:  Sleep       Date:  2003-11-01       Impact factor: 5.849

7.  [Chloral hydrate: a hypnotic best forgotten?].

Authors:  J Gauillard; S Cheref; M N Vacherontrystram; J C Martin
Journal:  Encephale       Date:  2002 May-Jun       Impact factor: 1.291

Review 8.  Comparative tolerability of newer agents for insomnia.

Authors:  Gary Zammit
Journal:  Drug Saf       Date:  2009       Impact factor: 5.606

Review 9.  A systematic review of valerian as a sleep aid: safe but not effective.

Authors:  Diana M Taibi; Carol A Landis; Heidi Petry; Michael V Vitiello
Journal:  Sleep Med Rev       Date:  2007-06       Impact factor: 11.609

Review 10.  Non-pharmacologic treatment of insomnia in persons with dementia.

Authors:  Denis Shub; Roham Darvishi; Mark E Kunik
Journal:  Geriatrics       Date:  2009-02
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