| Literature DB >> 2050473 |
C M Calthorpe1, I Grierson, R A Hitchings.
Abstract
Media conditioned by bovine corneal endothelium and scleral fibroblasts were found to induce the migration of bovine trabecular meshwork cells. The migrational activity had both chemokinetic (stimulated random motion) and chemotactic (directional migration) components. That produced by corneal endothelial cells had a markedly more potent effect. The relevance of these in vitro studies is discussed. Biochemically stimulated migration and loss of meshwork cells may be involved in the pathogenesis of glaucoma.Entities:
Mesh:
Substances:
Year: 1991 PMID: 2050473 DOI: 10.1007/bf00153926
Source DB: PubMed Journal: Int Ophthalmol ISSN: 0165-5701 Impact factor: 2.031