Literature DB >> 2050414

Evidence that Clostridium perfringens theta-toxin induces colloid-osmotic lysis of erythrocytes.

R W Harris1, P J Sims, R K Tweten.   

Abstract

Clostridium perfringens theta-toxin was shown to lyse target erythrocytes by a colloid-osmotic mechanism. Analysis showed the onset of lysis of erythrocytes by theta-toxin could be temporarily stabilized with 0.3 M sucrose. Flow cytometry analysis of the size distribution of theta-toxin-treated erythrocytes showed swelling of the erythrocytes prior to lysis.

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Year:  1991        PMID: 2050414      PMCID: PMC258038          DOI: 10.1128/iai.59.7.2499-2501.1991

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  13 in total

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Authors:  R K Tweten
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