OBJECTIVE: To identify the frequency of outpatient, non-hospitalized visits for respiratory syncytial virus (RSV) lower respiratory tract infection (LRI) among children and high-risk infants. STUDY DESIGN: Published studies that reported population-based rates of outpatient RSV illness were reviewed. In addition, we conducted a retrospective cohort study from a national claims database including preterm and full term infants born between April 2004 and April 2006 <6 months of age and continuously enrolled through their first RSV season. RESULTS: In the selected published studies, rates of outpatient RSV LRI were highest among infants and young children (ranging from 6.9 to 11 per 1,000 children age 1-4 years to 157.5 to 252.0 per 1,000 children age <1 year). In the cohort study, rates of outpatient RSV LRI among preterm infants <or=32 wGA or with chronic lung disease (CLD) ranged from 158.7 to 272.6 visits per 1,000 children. Rates for late preterm (33-36 wGA) infants ranged from 183.3 to 245.7 per 1,000, which was higher than full term infants (128.8 to 171.3 per 1,000). CONCLUSIONS: Approximately 1 in every 5 of high-risk infants will be affected during their first RSV season, which indicates a fairly high and unrecognized reservoir of disease. Outpatient RSV LRI visits increase with younger age and prematurity.
OBJECTIVE: To identify the frequency of outpatient, non-hospitalized visits for respiratory syncytial virus (RSV) lower respiratory tract infection (LRI) among children and high-risk infants. STUDY DESIGN: Published studies that reported population-based rates of outpatientRSV illness were reviewed. In addition, we conducted a retrospective cohort study from a national claims database including preterm and full term infants born between April 2004 and April 2006 <6 months of age and continuously enrolled through their first RSV season. RESULTS: In the selected published studies, rates of outpatientRSV LRI were highest among infants and young children (ranging from 6.9 to 11 per 1,000 children age 1-4 years to 157.5 to 252.0 per 1,000 children age <1 year). In the cohort study, rates of outpatientRSV LRI among preterm infants <or=32 wGA or with chronic lung disease (CLD) ranged from 158.7 to 272.6 visits per 1,000 children. Rates for late preterm (33-36 wGA) infants ranged from 183.3 to 245.7 per 1,000, which was higher than full term infants (128.8 to 171.3 per 1,000). CONCLUSIONS: Approximately 1 in every 5 of high-risk infants will be affected during their first RSV season, which indicates a fairly high and unrecognized reservoir of disease. OutpatientRSV LRI visits increase with younger age and prematurity.
Authors: Katherine L Anders; Hoa L Nguyen; Nguyet Minh Nguyen; Nguyen Thi Van Thuy; Nguyen Thi Hong Van; Nguyen Trong Hieu; Nguyen Thi Hong Tham; Phan Thi Thanh Ha; Le Bich Lien; Nguyen Van Vinh Chau; Vu Thi Ty Hang; H Rogier van Doorn; Cameron P Simmons Journal: Pediatr Infect Dis J Date: 2015-04 Impact factor: 2.129
Authors: Alma C van de Pol; Tom F W Wolfs; Carline E A Tacke; Cuno S P Uiterwaal; Johannes Forster; Anton M van Loon; Jan L L Kimpen; John W A Rossen; Nicolaas J G Jansen Journal: Pediatr Pulmonol Date: 2010-12-30
Authors: Joseph B Domachowske; Anis A Khan; Mark T Esser; Kathryn Jensen; Therese Takas; Tonya Villafana; Filip Dubovsky; M Pamela Griffin Journal: Pediatr Infect Dis J Date: 2018-09 Impact factor: 2.129