Ning Wu1, Christian Hirsch. 1. Department of Pediatric Dentistry and Primary Prevention, Department of Orthodontics, University of Leipzig, Nürnberger Strasse 57, Leipzig, Germany.
Abstract
OBJECTIVE: The etiology of temporomandibular disorders (TMD) remains unclear. The aim of this study was, by comparing the prevalence of TMD between adolescents of different ethnic origin, to examine whether certain genetic factors may play a role in causing TMD. SUBJECTS AND METHODS: We assessed the prevalence of TMD according to the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) in 1,058 subjects (561 German, 497 Chinese) aged 13 to 18 years from two general population samples. RESULTS: In total, the prevalence of RDC/TMD diagnoses was 13.9% (N = 147). The difference between German (13.0%, N = 73) and Chinese adolescents (14.9%, N = 74) was not statistically significant. After controlling for the effects of age, gender and orthodontic treatment using multivariable logistic regression analyses, the prevalence of RDC/TMD group II diagnoses (disc displacement) was lower in China than Germany (odds ratio [OR] = 0.5, 95% confidence interval [CI]: 0.3-0.8), whereas the prevalence of RDC/TMD pain diagnoses (group I, III) was higher in China (OR = 3.3, 95%-CI: 1.7-6.5). CONCLUSIONS: Our study reveals obvious differences in the prevalence of TMD between adolescents of different ethnic origins (Asians and Europeans). These differences cannot be attributed to cultural differences alone, which implies the involvement of genetic factors in the etiology of TMD.
OBJECTIVE: The etiology of temporomandibular disorders (TMD) remains unclear. The aim of this study was, by comparing the prevalence of TMD between adolescents of different ethnic origin, to examine whether certain genetic factors may play a role in causing TMD. SUBJECTS AND METHODS: We assessed the prevalence of TMD according to the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) in 1,058 subjects (561 German, 497 Chinese) aged 13 to 18 years from two general population samples. RESULTS: In total, the prevalence of RDC/TMD diagnoses was 13.9% (N = 147). The difference between German (13.0%, N = 73) and Chinese adolescents (14.9%, N = 74) was not statistically significant. After controlling for the effects of age, gender and orthodontic treatment using multivariable logistic regression analyses, the prevalence of RDC/TMD group II diagnoses (disc displacement) was lower in China than Germany (odds ratio [OR] = 0.5, 95% confidence interval [CI]: 0.3-0.8), whereas the prevalence of RDC/TMD pain diagnoses (group I, III) was higher in China (OR = 3.3, 95%-CI: 1.7-6.5). CONCLUSIONS: Our study reveals obvious differences in the prevalence of TMD between adolescents of different ethnic origins (Asians and Europeans). These differences cannot be attributed to cultural differences alone, which implies the involvement of genetic factors in the etiology of TMD.
Authors: Qing Yu; Yang Liu; Xi Chen; Duanjing Chen; Lu Xie; Xiao Hong; Xingyuan Wang; Haili Huang; Haiyang Yu Journal: Int Arch Occup Environ Health Date: 2015-01-17 Impact factor: 3.015
Authors: Paulo Correia de Melo Júnior; João Marcílio Coelho Netto Lins Aroucha; Manuela Arnaud; Maria Goretti de Souza Lima; Simone Guimarães Farias Gomes; Rosana Ximenes; Aronita Rosenblatt; Arnaldo de França Caldas Journal: PLoS One Date: 2019-02-08 Impact factor: 3.240