Literature DB >> 20502441

Skp2 knockout reduces cell proliferation and mouse body size: and prevents cancer?

Liang Zhu1.   

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Year:  2010        PMID： 20502441      PMCID： PMC2990532          DOI： 10.1038/cr.2010.71

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


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  15 in total

1.  An Rb-Skp2-p27 pathway mediates acute cell cycle inhibition by Rb and is retained in a partial-penetrance Rb mutant.

Authors:  Peng Ji; Hong Jiang; Katya Rekhtman; Joanna Bloom; Marina Ichetovkin; Michele Pagano; Liang Zhu
Journal:  Mol Cell       Date:  2004-10-08       Impact factor: 17.970

2.  Skp2 contains a novel cyclin A binding domain that directly protects cyclin A from inhibition by p27Kip1.

Authors:  Peng Ji; Luba Goldin; Hao Ren; Daqian Sun; Daniele Guardavaccaro; Michele Pagano; Liang Zhu
Journal:  J Biol Chem       Date:  2006-06-14       Impact factor: 5.157

Review 3.  Cellular senescence: when bad things happen to good cells.

Authors:  Judith Campisi; Fabrizio d'Adda di Fagagna
Journal:  Nat Rev Mol Cell Biol       Date:  2007-09       Impact factor: 94.444

4.  Structural basis of the Cks1-dependent recognition of p27(Kip1) by the SCF(Skp2) ubiquitin ligase.

Authors:  Bing Hao; Ning Zheng; Brenda A Schulman; Geng Wu; Julie J Miller; Michele Pagano; Nikola P Pavletich
Journal:  Mol Cell       Date:  2005-10-07       Impact factor: 17.970

5.  F-box protein Skp2: a novel transcriptional target of E2F.

Authors:  L Zhang; C Wang
Journal:  Oncogene       Date:  2006-04-27       Impact factor: 9.867

6.  Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit.

Authors:  Ulrich K Binné; Marie K Classon; Frederick A Dick; Wenyi Wei; Michael Rape; William G Kaelin; Anders M Näär; Nicholas J Dyson
Journal:  Nat Cell Biol       Date:  2006-12-24       Impact factor: 28.824

7.  Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication.

Authors:  K Nakayama; H Nagahama; Y A Minamishima; M Matsumoto; I Nakamichi; K Kitagawa; M Shirane; R Tsunematsu; T Tsukiyama; N Ishida; M Kitagawa; K Nakayama; S Hatakeyama
Journal:  EMBO J       Date:  2000-05-02       Impact factor: 11.598

8.  A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 and S phase.

Authors:  N P Malek; H Sundberg; S McGrew; K Nakayama; T R Kyriakides; J M Roberts; T R Kyriakidis
Journal:  Nature       Date:  2001-09-20       Impact factor: 49.962

9.  Skp2 suppresses p53-dependent apoptosis by inhibiting p300.

Authors:  Mayumi Kitagawa; Sang Hyun Lee; Frank McCormick
Journal:  Mol Cell       Date:  2008-02-01       Impact factor: 17.970

Review 10.  Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer.

Authors:  David Frescas; Michele Pagano
Journal:  Nat Rev Cancer       Date:  2008-06       Impact factor: 60.716
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  12 in total

1.  p63 maintains keratinocyte proliferative capacity through regulation of Skp2-p130 levels.

Authors:  Simon S McDade; Daksha Patel; Dennis J McCance
Journal:  J Cell Sci       Date:  2011-04-21       Impact factor: 5.285

2.  microRNA-200b and microRNA-200c promote colorectal cancer cell proliferation via targeting the reversion-inducing cysteine-rich protein with Kazal motifs.

Authors:  Yi Pan; Hongwei Liang; Weixu Chen; Hongjie Zhang; Nan Wang; Feng Wang; Suyang Zhang; Yanqing Liu; Chihao Zhao; Xin Yan; Junfeng Zhang; Chen-Yu Zhang; Hongwei Gu; Ke Zen; Xi Chen
Journal:  RNA Biol       Date:  2015       Impact factor: 4.652

3.  Domain-specific c-Myc ubiquitylation controls c-Myc transcriptional and apoptotic activity.

Authors:  Qin Zhang; Erick Spears; David N Boone; Zhaoliang Li; Mark A Gregory; Stephen R Hann
Journal:  Proc Natl Acad Sci U S A       Date:  2012-12-31       Impact factor: 11.205

4.  The retinoblastoma protein selectively represses E2F1 targets via a TAAC DNA element during cellular senescence.

Authors:  Tianda Chen; Lixiang Xue; Jing Niu; Liwei Ma; Na Li; Xiaoxiao Cao; Qian Li; Meng Wang; Wenting Zhao; Guodong Li; Jiamu Wang; Tanjun Tong
Journal:  J Biol Chem       Date:  2012-09-06       Impact factor: 5.157

5.  Beta-estradiol attenuates hypoxic pulmonary hypertension by stabilizing the expression of p27kip1 in rats.

Authors:  Dun-Quan Xu; Ying Luo; Yi Liu; Jing Wang; Bo Zhang; Min Xu; Yan-Xia Wang; Hai-Ying Dong; Ming-Qing Dong; Peng-Tao Zhao; Wen Niu; Man-Ling Liu; Yu-Qi Gao; Zhi-Chao Li
Journal:  Respir Res       Date:  2010-12-24

6.  Ezetimibe prevents the development of non‑alcoholic fatty liver disease induced by high‑fat diet in C57BL/6J mice.

Authors:  Xiang Wang; Qiaohua Ren; Tao Wu; Yong Guo; Yong Liang; Subo Liu
Journal:  Mol Med Rep       Date:  2014-10-10       Impact factor: 2.952

7.  The Drosophila F-box protein dSkp2 regulates cell proliferation by targeting Dacapo for degradation.

Authors:  Wen Dui; Bin Wei; Feng He; Wei Lu; Changqing Li; Xuehong Liang; Jun Ma; Renjie Jiao
Journal:  Mol Biol Cell       Date:  2013-04-03       Impact factor: 4.138

8.  Transforming growth factor β1 increases p27 levels via synthesis and degradation mechanisms in the hyperproliferative gastric epithelium in rats.

Authors:  Ana P Z P Fiore; Luciana H Osaki; Patricia Gama
Journal:  PLoS One       Date:  2014-07-07       Impact factor: 3.240

9.  E3-ligase Skp2 predicts poor prognosis and maintains cancer stem cell pool in nasopharyngeal carcinoma.

Authors:  Jing Wang; Ying Huang; Zhong Guan; Jia-Liang Zhang; Hong-Kai Su; Wei Zhang; Cai-Feng Yue; Min Yan; Su Guan; Quentin Qiang Liu
Journal:  Oncotarget       Date:  2014-07-30

10.  Bortezomib-mediated downregulation of S-phase kinase protein-2 (SKP2) causes apoptotic cell death in chronic myelogenous leukemia cells.

Authors:  Ahmad Iskandarani; Ajaz A Bhat; Kodappully S Siveen; Kirti S Prabhu; Shilpa Kuttikrishnan; Muzammil A Khan; Roopesh Krishnankutty; Michal Kulinski; Rihab R Nasr; Ramzi M Mohammad; Shahab Uddin
Journal:  J Transl Med       Date:  2016-03-09       Impact factor: 5.531
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