Literature DB >> 20499094

Malaria parasite genome scan: insights into antimalarial resistance.

Bhavna Gupta1, Gauri Awasthi, Aparup Das.   

Abstract

Genome scan and genotype-phenotype association study offer excellent opportunities to unearth drug/vaccine targets in human pathogens including malaria parasites. A recently conducted such study in worldwide isolates in the most devastating malaria parasite Plasmodium falciparum has reported important genomic information on genetic basis of antimalarial resistance. Several unknown genes were also found to be under strong influence of natural selection. The findings provide important insights into the malaria parasite genome evolution in general and to use this information to develop more focused malaria control strategies, in particular.

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Year:  2010        PMID： 20499094     DOI： 10.1007/s00436-010-1917-8

Source DB:  PubMed          Journal:  Parasitol Res        ISSN： 0932-0113            Impact factor:   2.289


  29 in total

1.  Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance.

Authors:  D A Fidock; T Nomura; A K Talley; R A Cooper; S M Dzekunov; M T Ferdig; L M Ursos; A B Sidhu; B Naudé; K W Deitsch; X Z Su; J C Wootton; P D Roepe; T E Wellems
Journal:  Mol Cell       Date:  2000-10       Impact factor: 17.970

2.  Evidence of artemisinin-resistant malaria in western Cambodia.

Authors:  Harald Noedl; Youry Se; Kurt Schaecher; Bryan L Smith; Duong Socheat; Mark M Fukuda
Journal:  N Engl J Med       Date:  2008-12-08       Impact factor: 91.245

3.  Geographic patterns of Plasmodium falciparum drug resistance distinguished by differential responses to amodiaquine and chloroquine.

Authors:  Juliana Martha Sá; Olivia Twu; Karen Hayton; Sahily Reyes; Michael P Fay; Pascal Ringwald; Thomas E Wellems
Journal:  Proc Natl Acad Sci U S A       Date:  2009-11-02       Impact factor: 11.205

4.  Evaluation of chloroquine (CQ) and sulphadoxine/pyrimethamine (SP) therapy in uncomplicated falciparum malaria in Indo-Myanmar border areas.

Authors:  P K Mohapatra; Anil Prakash; K Taison; K Negmu; A C Gohain; N S Namchoom; D Wange; D R Bhattacharyya; B K Goswami; B K Borgohain; J Mahanta
Journal:  Trop Med Int Health       Date:  2005-05       Impact factor: 2.622

5.  Genome variation and evolution of the malaria parasite Plasmodium falciparum.

Authors:  Daniel C Jeffares; Arnab Pain; Andrew Berry; Anthony V Cox; James Stalker; Catherine E Ingle; Alan Thomas; Michael A Quail; Kyle Siebenthall; Anne-Catrin Uhlemann; Sue Kyes; Sanjeev Krishna; Chris Newbold; Emmanouil T Dermitzakis; Matthew Berriman
Journal:  Nat Genet       Date:  2006-12-10       Impact factor: 38.330

6.  Genome-wide variation and identification of vaccine targets in the Plasmodium falciparum genome.

Authors:  Jianbing Mu; Philip Awadalla; Junhui Duan; Kate M McGee; Jon Keebler; Karl Seydel; Gilean A T McVean; Xin-zhuan Su
Journal:  Nat Genet       Date:  2006-12-10       Impact factor: 38.330

7.  Whole genome scan to detect chromosomal regions affecting multiple traits in dairy cattle.

Authors:  C Schrooten; M C A M Bink; H Bovenhuis
Journal:  J Dairy Sci       Date:  2004-10       Impact factor: 4.034

8.  Artemisinin resistance in Plasmodium falciparum malaria.

Authors:  Arjen M Dondorp; François Nosten; Poravuth Yi; Debashish Das; Aung Phae Phyo; Joel Tarning; Khin Maung Lwin; Frederic Ariey; Warunee Hanpithakpong; Sue J Lee; Pascal Ringwald; Kamolrat Silamut; Mallika Imwong; Kesinee Chotivanich; Pharath Lim; Trent Herdman; Sen Sam An; Shunmay Yeung; Pratap Singhasivanon; Nicholas P J Day; Niklas Lindegardh; Duong Socheat; Nicholas J White
Journal:  N Engl J Med       Date:  2009-07-30       Impact factor: 91.245

9.  Plasmodium falciparum and Plasmodium vivax: so similar, yet very different.

Authors:  Aparup Das; Meenu Sharma; Bhavna Gupta; Aditya Prasad Dash
Journal:  Parasitol Res       Date:  2009-06-20       Impact factor: 2.289

10.  Plasmodium falciparum genome-wide scans for positive selection, recombination hot spots and resistance to antimalarial drugs.

Authors:  Jianbing Mu; Rachel A Myers; Hongying Jiang; Shengfa Liu; Stacy Ricklefs; Michael Waisberg; Kesinee Chotivanich; Polrat Wilairatana; Srivicha Krudsood; Nicholas J White; Rachanee Udomsangpetch; Liwang Cui; May Ho; Fengzhen Ou; Haibo Li; Jianping Song; Guoqiao Li; Xinhua Wang; Suon Seila; Sreng Sokunthea; Duong Socheat; Daniel E Sturdevant; Stephen F Porcella; Rick M Fairhurst; Thomas E Wellems; Philip Awadalla; Xin-zhuan Su
Journal:  Nat Genet       Date:  2010-01-31       Impact factor: 38.330
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  3 in total

1.  Measuring resistant-genotype transmission of malaria parasites: challenges and prospects.

Authors:  Rashad Abdul-Ghani; Hoda F Farag; Amal F Allam; Ahmed A Azazy
Journal:  Parasitol Res       Date:  2014-02-22       Impact factor: 2.289

Review 2.  Malaria evolution in South Asia: knowledge for control and elimination.

Authors:  Krishnamoorthy Narayanasamy; Laura Chery; Analabha Basu; Manoj T Duraisingh; Ananias Escalante; Joseph Fowble; Jennifer L Guler; Thurston Herricks; Ashwani Kumar; Partha Majumder; Jennifer Maki; Anjali Mascarenhas; Janneth Rodrigues; Bikram Roy; Somdutta Sen; Jayanthi Shastri; Joseph Smith; Neena Valecha; John White; Pradipsinh K Rathod
Journal:  Acta Trop       Date:  2012-01-14       Impact factor: 3.112

Review 3.  Genetics of chloroquine-resistant malaria: a haplotypic view.

Authors:  Gauri Awasthi; Aparup Das
Journal:  Mem Inst Oswaldo Cruz       Date:  2013-12       Impact factor: 2.743
  3 in total

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