Literature DB >> 20498312

In vitro activity of azithromycin against nontyphoidal Salmonella enterica.

Marianne Gunell1, Pirkko Kotilainen, Jari Jalava, Pentti Huovinen, Anja Siitonen, Antti J Hakanen.   

Abstract

The in vitro activity of azithromycin against 1,237 nontyphoidal Salmonella enterica isolates collected from Finnish patients between 2003 and 2008 was investigated. Only 24 (1.9%) of the isolates tested and 15 (5.1%) of the 294 isolates with reduced fluoroquinolone susceptibility had azithromycin MICs of >or=32 microg/ml. These data show that azithromycin has good in vitro activity against nontyphoidal S. enterica, and thus, it may be a good candidate for clinical treatment studies of salmonellosis.

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Year:  2010        PMID： 20498312      PMCID： PMC2916314          DOI： 10.1128/AAC.01678-09

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  29 in total

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