Literature DB >> 2049687

Disopyramide as a negative inotrope in obstructive cardiomyopathy in children.

W J Duncan1, M J Tyrrell, B B Bharadwaj.   

Abstract

Two children with left ventricular outflow tract obstruction due to myocardial hypertrophy received oral disopyramide as a negative inotrope. Both showed rapid improvement in clinical signs and by echo Doppler examination. Nearly complete abolition of severe left ventricular outflow tract obstruction was documented in each case. This experience may prompt further application of disopyramide as a therapeutic agent to relieve dynamic muscular subaortic obstruction in children.

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Year:  1991        PMID： 2049687

Source DB:  PubMed          Journal:  Can J Cardiol        ISSN： 0828-282X            Impact factor:   5.223


  3 in total

1.  An equation to predict the changes in peak left ventricular pressure in hypertrophic obstructive cardiomyopathy after treatment: application to the administration of disopyramide.

Authors:  K Niki; M Sugawara; S Tanino; K Iwade; S Hosoda; H Kasanuki
Journal:  Heart Vessels       Date:  1999       Impact factor: 2.037

2.  Disopyramide improves the balance between myocardial oxygen supply and demand in patients with hypertrophic obstructive cardiomyopathy.

Authors:  K Niki; M Sugawara; R Asano; T Oka; Y Kondoh; S Tanino; K Iwade; N Magosaki; H Kasanuki; S Hosoda
Journal:  Heart Vessels       Date:  1997       Impact factor: 2.037

3.  Hypertrophic Cardiomyopathy.

Authors: 
Journal:  Curr Treat Options Cardiovasc Med       Date:  1999-10
  3 in total

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