Literature DB >> 20496532

Gastrointestinal and liver tumours and public health in Europe.

T Milosavljevic1, M Kostic-Milosavljevic, I Jovanovic, M Krstic.   

Abstract

STATE OF THE ART: Europe comprises only one eighth of the total world population but has around one quarter of the global total of cancer cases--some 3.2 million new patients per year. While the disproportionate cancer burden is readily apparent, the disease patterns in Europe cannot simply be generalized--overall cancer incidence and mortality rates vary at least two-fold between European countries and the differences are often far greater for specific cancers. With 1.7 million deaths each year, cancer currently represents the second most important cause of death in Europe. The range of survival rates is similarly wide. For individual cancers, the variation across Europe is even greater. This reflects a wide range of social and epidemiological factors in different countries: cancer prevention programmes; screening programmes; cancer control plans; individual lifestyles and occupational exposures; the existence and accessibility of health-care facilities and technological infrastructure; and the availability of human, financial and material resources for health and economic development. Europe has some of the richest countries in the world, but also some of the poorest. In 2002, 168 million people were living below the poverty line, about 46% of the European population. The time trends in cancer risk also vary between European countries and some cancers show different trends between men and women, or young and old, or poor and rich. The public health profile of cancer in Europe is complex. Trends in the incidence and mortality rates are also influenced by successes in health promotion (e.g. tobacco control), efficient screening (e.g. breast, bowel, cervix) and better treatment. These have been reflected in lower incidence, reduced mortality, higher survival, improved life expectancy and a better quality of life for cancer survivors.
CONCLUSIONS: Cancer of the gastrointestinal (GI) tract is the most common cancer in Europe. More than half of GI cancer cases arise from the colon. They can remain asymptomatic until late in the natural history of the disease, and as this is the stage at which they can be cured, screening has been advocated for well members of the population and surveillance for those with conditions predisposing to cancer.

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Mesh:

Year:  2010        PMID: 20496532

Source DB:  PubMed          Journal:  Eur Rev Med Pharmacol Sci        ISSN: 1128-3602            Impact factor:   3.507


  6 in total

1.  RNAi knockdown of PIK3CA preferentially inhibits invasion of mutant PIK3CA cells.

Authors:  Xin-Ke Zhou; Sheng-Song Tang; Gao Yi; Min Hou; Jin-Hui Chen; Bo Yang; Ji-Fang Liu; Zhi-Min He
Journal:  World J Gastroenterol       Date:  2011-08-28       Impact factor: 5.742

2.  Study of risk factors for gastric cancer by populational databases analysis.

Authors:  Fangio Ferrari; Marco Antonio Moura Reis
Journal:  World J Gastroenterol       Date:  2013-12-28       Impact factor: 5.742

3.  Understanding the symptom experience of patients with gastrointestinal cancers in the first year following diagnosis: findings from a qualitative longitudinal study.

Authors:  J Ellis; S G Brearley; O Craven; A Molassiotis
Journal:  J Gastrointest Cancer       Date:  2013-03

4.  Bone metastases in gastrointestinal cancer.

Authors:  Fabienne Portales; Simon Thézenas; Emmanuelle Samalin; Eric Assenat; Thibault Mazard; Marc Ychou
Journal:  Clin Exp Metastasis       Date:  2014-11-09       Impact factor: 5.150

5.  A functional NQO1 609C>T polymorphism and risk of gastrointestinal cancers: a meta-analysis.

Authors:  Hongping Yu; Hongliang Liu; Li-E Wang; Qingyi Wei
Journal:  PLoS One       Date:  2012-01-17       Impact factor: 3.240

6.  Retrospective study of predictors of bone metastasis in colorectal cancer patients.

Authors: 
Journal:  J Bone Oncol       Date:  2017-10-31       Impact factor: 4.072

  6 in total

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