Literature DB >> 20496259

Intraductal therapy for the prevention of breast cancer.

Lisa Jacobs1, Saraswati Sukumar, Vered Stearns.   

Abstract

Patients at high risk for developing breast cancer and those with early stage breast cancer may have treatment options in addition to systemic therapy for the prevention and treatment of this disease in the near future. Methods of intraductal diagnosis and treatment of breast cancer, including nipple aspiration, ductal lavage and ductoscopy, are discussed in this review. Advances in this field include improvements in equipment and techniques, more reliable biomarker assessment and improved targeted therapies. As a result of these advances, intraductal treatment in high-risk populations is being investigated in clinical trials.

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Year:  2010        PMID： 20496259

Source DB:  PubMed          Journal:  Curr Opin Investig Drugs        ISSN： 1472-4472


  10 in total

1.  Preclinical and clinical evaluation of intraductally administered agents in early breast cancer.

Authors:  Vered Stearns; Tsuyoshi Mori; Lisa K Jacobs; Nagi F Khouri; Edward Gabrielson; Takahiro Yoshida; Scott L Kominsky; David L Huso; Stacie Jeter; Penny Powers; Karineh Tarpinian; Regina J Brown; Julie R Lange; Michelle A Rudek; Zhe Zhang; Theodore N Tsangaris; Saraswati Sukumar
Journal:  Sci Transl Med       Date:  2011-10-26       Impact factor: 17.956

2.  Intraductally administered pegylated liposomal doxorubicin reduces mammary stem cell function in the mammary gland but in the long term, induces malignant tumors.

Authors:  Yong Soon Chun; Takahiro Yoshida; Tsuyoshi Mori; David L Huso; Zhe Zhang; Vered Stearns; Brandy Perkins; Richard J Jones; Saraswati Sukumar
Journal:  Breast Cancer Res Treat       Date:  2012-07-01       Impact factor: 4.872

3.  Intraductal administration of transferrin receptor-targeted immunotoxin clears ductal carcinoma in situ in mouse models of breast cancer-a preclinical study.

Authors:  Guannan Wang; Alok Kumar; Wanjun Ding; Preethi Korangath; Tapan Bera; Junxia Wei; Priya Pai; Kathleen Gabrielson; Ira Pastan; Saraswati Sukumar
Journal:  Proc Natl Acad Sci U S A       Date:  2022-06-08       Impact factor: 12.779

4.  Intraductal administration of a polymeric nanoparticle formulation of curcumin (NanoCurc) significantly attenuates incidence of mammary tumors in a rodent chemical carcinogenesis model: Implications for breast cancer chemoprevention in at-risk populations.

Authors:  Yong Soon Chun; Savita Bisht; Venugopal Chenna; Dipankar Pramanik; Takahiro Yoshida; Seung-Mo Hong; Roeland F de Wilde; Zhe Zhang; David L Huso; Ming Zhao; Michelle A Rudek; Vered Stearns; Anirban Maitra; Saraswati Sukumar
Journal:  Carcinogenesis       Date:  2012-07-25       Impact factor: 4.944

5.  Intraductal therapy of ductal carcinoma in situ: a presurgery study.

Authors:  M Ellen Mahoney; Eva J Gordon; Jian Yu Rao; Yusheng Jin; Nola Hylton; Susan M Love
Journal:  Clin Breast Cancer       Date:  2013-05-09       Impact factor: 3.225

6.  Breast intraductal nanoformulations for treating ductal carcinoma in situ II: Dose de-escalation using a slow releasing/slow bioconverting prodrug strategy.

Authors:  Firas Al-Zubaydi; Dayuan Gao; Dipti Kakkar; Shike Li; Jennifer Holloway; Zoltan Szekely; Nancy Chan; Shicha Kumar; Hatem E Sabaawy; Susan Love; Patrick J Sinko
Journal:  Drug Deliv Transl Res       Date:  2021-02-15       Impact factor: 4.617

7.  Intraductal administration of N-methyl-N-nitrosourea as a novel rodent mammary tumor model.

Authors:  Dongcheng Gao; Jianhua Liu; Jingping Yuan; Juan Wu; Xinwen Kuang; Deguang Kong; Weijie Zheng; Guannan Wang; Saraswati Sukumar; Yi Tu; Chuang Chen; Shengrong Sun
Journal:  Ann Transl Med       Date:  2021-04

8.  Intraductal injection for localized drug delivery to the mouse mammary gland.

Authors:  Silva Krause; Amy Brock; Donald E Ingber
Journal:  J Vis Exp       Date:  2013-10-04       Impact factor: 1.355

9.  Ductal tree ablation by local delivery of ethanol prevents tumor formation in an aggressive mouse model of breast cancer.

Authors:  Elizabeth Kenyon; Jennifer J Westerhuis; Maximilian Volk; Jeremy Hix; Shatadru Chakravarty; Ethan Claucherty; Erin Zaluzec; Lisa Ramsey; Zach Madaj; Galen Hostetter; Bryn Eagleson; Erik Shapiro; Anna Moore; Lorenzo F Sempere
Journal:  Breast Cancer Res       Date:  2019-11-28       Impact factor: 6.466

10.  Examination of Duct Physiology in the Human Mammary Gland.

Authors:  Dixie Mills; Ameer Gomberawalla; Eva J Gordon; Julie Tondre; Mitra Nejad; Tinh Nguyen; Janice M Pogoda; Jianyu Rao; Robert Chatterton; Susanne Henning; Susan M Love
Journal:  PLoS One       Date:  2016-04-13       Impact factor: 3.240
  10 in total

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