| Literature DB >> 20495 |
R J Sturgeon, C Flanagan, D V Naik, S G Schulman.
Abstract
The adsorption of doxorubicin hydrochloride, a potent antitumor agent, on solid tribasic calcium phosphate was studied in vitro. A Langmuir adsorption isotherm at pH 7.4 and the maximum adsorption capacity of tribasic calcium phosphate were established. Tribasic calcium phosphate was chosen as a model for solid bone samples, which are stained with doxorubicin in patients who have received long-term doxorubicin therapy.Entities:
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Year: 1977 PMID： 20495 DOI： 10.1002/jps.2600660940
Source DB: PubMed Journal: J Pharm Sci ISSN： 0022-3549 Impact factor: 3.534