Literature DB >> 20494382

Biotransformation of 7alpha-hydroxy- and 7-oxo-ent-atis-16-ene derivatives by the fungus Gibberella fujikuroi.

Braulio M Fraga1, Pedro Gonzalez, Victoria Gonzalez-Vallejo, Ricardo Guillermo, Luz N Diaz.   

Abstract

The microbiological transformation of 7alpha,19-dihydroxy-ent-atis-16-ene by the fungus Gibberella fujikuroi gave 19-hydroxy-7-oxo-ent-atis-16-ene, 13(R),19-dihydroxy-7-oxo-ent-atis-16-ene, 7alpha,11beta,19-trihydroxy-ent-atis-16-ene and 7alpha,16beta,19-trihydroxy-ent-atis-16-ene, while the incubation of 19-hydroxy-7-oxo-ent-atis-16-ene afforded 13(R),19-dihydroxy-7-oxo-ent-atis-16-ene and 16beta,17-dihydroxy-7-oxo-ent-atisan-19-al. The biotransformation of 7-oxo-ent-atis-16-en-19-oic acid gave 6beta-hydroxy-7-oxo-ent-atis-16-en-19-oic acid, 6beta,16beta,17-trihydroxy-7-oxo-19-nor-ent-atis-4(18)-ene and 3beta,7alpha-dihydroxy-6-oxo-ent-atis-16-en-19-oic acid. Copyright 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID: 20494382     DOI: 10.1016/j.phytochem.2010.04.024

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  1 in total

1.  The incubation of 13α,17-dihydroxystemodane with Cephalosporium aphidicola.

Authors:  Braulio M Fraga; Ricardo Guillermo; Melchor G Hernández; María C Chamy; Juan A Garbarino
Journal:  Molecules       Date:  2012-02-09       Impact factor: 4.411

  1 in total

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