Literature DB >> 2049380

The d-spacing of collagen from mitral heart valves changes with ageing, but not with collagen type III content.

V J James1, J F McConnell, M Capel.   

Abstract

A low angle X-ray diffraction study of normal and myxomatous human heart valves has been carried out using a Synchrotron radiation source. This study has shown a slight progressive decrease in the d-spacing of the collagen with age. Despite suggestions reported in the literature, no significant relative change was observed in the d-spacing with the increase in the percentage of collagen type III from 24% in normal to 31% in myxomatous heart valves.

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Year:  1991        PMID: 2049380     DOI: 10.1016/0167-4838(91)90086-f

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


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