| Literature DB >> 20493007 |
Abstract
Pregnenolone, dehydroepiandrosterone and their sulfate esters have been characterized in the rat brain. Their formation or accumulation depend on in situ mechanisms unrelated to the peripheral endocrine glands. Although their functions are still poorly understood, they may affect the brain by metabolism to sex steroid hormones and they may be functionally related to sexual behavior, possibly through direct modulations of the firing rates of neurons.Entities:
Year: 1985 PMID: 20493007 DOI: 10.1016/0197-0186(85)90143-3
Source DB: PubMed Journal: Neurochem Int ISSN: 0197-0186 Impact factor: 3.921