Literature DB >> 20493007

Neuro-steroids: 3?-hydroxy-?(5)-derivatives in the rodent brain.

P Robel1, E E Baulieu.   

Abstract

Pregnenolone, dehydroepiandrosterone and their sulfate esters have been characterized in the rat brain. Their formation or accumulation depend on in situ mechanisms unrelated to the peripheral endocrine glands. Although their functions are still poorly understood, they may affect the brain by metabolism to sex steroid hormones and they may be functionally related to sexual behavior, possibly through direct modulations of the firing rates of neurons.

Entities:  

Year:  1985        PMID: 20493007     DOI: 10.1016/0197-0186(85)90143-3

Source DB:  PubMed          Journal:  Neurochem Int        ISSN: 0197-0186            Impact factor:   3.921


  16 in total

Review 1.  Gonadal steroids and neuronal function.

Authors:  R Alonso; I López-Coviella
Journal:  Neurochem Res       Date:  1998-05       Impact factor: 3.996

2.  2-Phenyl-imidazo[1,2-a]pyridine derivatives as ligands for peripheral benzodiazepine receptors: stimulation of neurosteroid synthesis and anticonflict action in rats.

Authors:  M Serra; P Madau; M F Chessa; M Caddeo; E Sanna; G Trapani; M Franco; G Liso; R H Purdy; M L Barbaccia; G Biggio
Journal:  Br J Pharmacol       Date:  1999-05       Impact factor: 8.739

Review 3.  Progesterone as a neurosteroid: actions within the nervous system.

Authors:  E E Baulieu; M Schumacher; H Koenig; I Jung-Testas; Y Akwa
Journal:  Cell Mol Neurobiol       Date:  1996-04       Impact factor: 5.046

Review 4.  A novel aspect of the cerebellum: biosynthesis of neurosteroids in the Purkinje cell.

Authors:  Kazuyoshi Tsutsui; Hirotaka Sakamoto; Kazuyoshi Ukena
Journal:  Cerebellum       Date:  2003       Impact factor: 3.847

Review 5.  Neurosteroids in the Purkinje cell: biosynthesis, mode of action and functional significance.

Authors:  Kazuyoshi Tsutsui
Journal:  Mol Neurobiol       Date:  2008-06-03       Impact factor: 5.590

6.  Long-term incubation with mifepristone (MLTI) increases the spine density in developing Purkinje cells: new insights into progesterone receptor mechanisms.

Authors:  Lisa Wessel; Ajeesh Balakrishnan-Renuka; Corinna Henkel; Helmut E Meyer; Karl Meller; Beate Brand-Saberi; Carsten Theiss
Journal:  Cell Mol Life Sci       Date:  2013-08-28       Impact factor: 9.261

7.  Regulation of neurosteroid biosynthesis by neurotransmitters and neuropeptides.

Authors:  Jean Luc Do Rego; Jae Young Seong; Delphine Burel; Jerôme Leprince; David Vaudry; Van Luu-The; Marie-Christine Tonon; Kazuyoshi Tsutsui; Georges Pelletier; Hubert Vaudry
Journal:  Front Endocrinol (Lausanne)       Date:  2012-01-24       Impact factor: 5.555

8.  7α-hydroxypregnenolone, a new key regulator of locomotor activity of vertebrates: identification, mode of action, and functional significance.

Authors:  Kazuyoshi Tsutsui; Shogo Haraguchi; Masahiro Matsunaga; Kazuhiko Inoue; Hubert Vaudry
Journal:  Front Endocrinol (Lausanne)       Date:  2010-12-24       Impact factor: 5.555

9.  Oxidative Stress-Mediated Brain Dehydroepiandrosterone (DHEA) Formation in Alzheimer's Disease Diagnosis.

Authors:  Georges Rammouz; Laurent Lecanu; Vassilios Papadopoulos
Journal:  Front Endocrinol (Lausanne)       Date:  2011-11-08       Impact factor: 5.555

10.  Neurosteroid biosynthesis in the brain of amphibians.

Authors:  Hubert Vaudry; Jean-Luc Do Rego; Delphine Burel; Van Luu-The; Georges Pelletier; David Vaudry; Kazuyoshi Tsutsui
Journal:  Front Endocrinol (Lausanne)       Date:  2011-11-30       Impact factor: 5.555

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