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Literature DB >> 2049235

The pharmacokinetics of postoperative intravenous ketorolac tromethamine in children.

Abstract

Ketorolac tromethamine (0.5 mg kg-1) was given intravenously to 10 children (age 4-8 years) after minor surgery. Values of steady-state volume of distribution and plasma clearance were approximately two times higher than those in adults but values of elimination half-life were similar.

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Year: 1991 PMID： 2049235 PMCID： PMC1368388 DOI： 10.1111/j.1365-2125.1991.tb05510.x

Source DB: PubMed Journal: Br J Clin Pharmacol ISSN： 0306-5251 Impact factor: 4.335

7 in total

1. Pharmacokinetics of ketorolac tromethamine in humans after intravenous, intramuscular and oral administration.

Authors: D Jung; E Mroszczak; L Bynum
Journal: Eur J Clin Pharmacol Date: 1988 Impact factor: 2.953

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Journal: Eur J Clin Pharmacol Date: 1981 Impact factor: 2.953

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Authors: S S Bloomfield; J Mitchell; G B Cissell; T P Barden; J P Yee
Journal: Pharmacotherapy Date: 1986 Sep-Oct Impact factor: 4.705

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Authors: J P Yee; J E Koshiver; C Allbon; C R Brown
Journal: Pharmacotherapy Date: 1986 Sep-Oct Impact factor: 4.705

6. Measurement of pain in children with self-reporting and behavioral assessment.

Authors: E L Maunuksela; K T Olkkola; R Korpela
Journal: Clin Pharmacol Ther Date: 1987-08 Impact factor: 6.875

7. Ketorolac tromethamine absorption, distribution, metabolism, excretion, and pharmacokinetics in animals and humans.

Authors: E J Mroszczak; F W Lee; D Combs; F H Sarnquist; B L Huang; A T Wu; L G Tokes; M L Maddox; D K Cho
Journal: Drug Metab Dispos Date: 1987 Sep-Oct Impact factor: 3.922

7 in total

12 in total

Review 1. Risks and benefits of nonsteroidal anti-inflammatory drugs in children: a comparison with paracetamol.

Authors: C Litalien; E Jacqz-Aigrain
Journal: Paediatr Drugs Date: 2001 Impact factor: 3.022

Review 2. Implementation of a standardized pain management in a pediatric surgery unit.

Authors: B Messerer; A Gutmann; A Weinberg; A Sandner-Kiesling
Journal: Pediatr Surg Int Date: 2010-07-13 Impact factor: 1.827

Review 3. Ketorolac. A reappraisal of its pharmacodynamic and pharmacokinetic properties and therapeutic use in pain management.

Authors: J C Gillis; R N Brogden
Journal: Drugs Date: 1997-01 Impact factor: 9.546

Review 4. Ketorolac for postoperative pain management in children.

Authors: J B Forrest; E L Heitlinger; S Revell
Journal: Drug Saf Date: 1997-05 Impact factor: 5.606

5. Ketorolac tromethamine: stereo-specific pharmacokinetics and single-dose use in postoperative infants aged 2-6 months.

Authors: Anne M Lynn; Heidi Bradford; Eric D Kantor; Marilee Andrew; Paolo Vicini; Gail D Anderson
Journal: Paediatr Anaesth Date: 2010-12-29 Impact factor: 2.556

6. Enantiomer-specific ketorolac pharmacokinetics in young women, including pregnancy and postpartum period.

Authors: Aida Kulo; Anne Smits; Sanita Maleškić; Marc Van de Velde; Kristel Van Calsteren; Jan De Hoon; Rene Verbesselt; Jan Deprest; Karel Allegaert
Journal: Bosn J Basic Med Sci Date: 2017-02-21 Impact factor: 3.363

7. Comparative effects of three doses of intravenous ketorolac or morphine on emesis and analgesia for restorative dental surgery in children.

Authors: J P Purday; C C Reichert; P M Merrick
Journal: Can J Anaesth Date: 1996-03 Impact factor: 5.063