Helen C Fox1, Keri L Bergquist, Gu Peihua, Sinha Rajita. 1. Department of Psychiatry, Yale University School of Medicine, The Yale Stress Center, New Haven, Connecticut 06519, USA. helen.fox@yale.edu
Abstract
BACKGROUND: Alcohol addiction may reflect adaptations to stress, reward, and regulatory brain systems. While extensive research has identified both stress and impulsivity as independent risk factors for drinking, few studies have assessed the interactive relationship between stress and impulsivity in terms of hazardous drinking within a community sample of regular drinkers. METHODS: One hundred and thirty regular drinkers (56M/74F) from the local community were assessed for hazardous and harmful patterns of alcohol consumption using the Alcohol Use Disorders Identification Test (AUDIT). All participants were also administered the Barratt Impulsiveness Scale (BIS-11) as a measure of trait impulsivity and the Cumulative Stress/Adversity Checklist (CSC) as a comprehensive measure of cumulative adverse life events. Standard multiple regression models were used to ascertain the independent and interactive nature of both overall stress and impulsivity as well as specific types of stress and impulsivity on hazardous and harmful drinking. RESULTS: Recent life stress, cumulative traumatic stress, overall impulsivity, and nonplanning-related impulsivity as well as cognitive and motor-related impulsivity were all independently predictive of AUDIT scores. However, the interaction between cumulative stress and total impulsivity scores accounted for a significant amount of the variance, indicating that a high to moderate number of adverse events and a high trait impulsivity rating interacted to affect greater AUDIT scores. The subscale of cumulative life trauma accounted for the most variance in AUDIT scores among the stress and impulsivity subscales. CONCLUSIONS: Findings highlight the interactive relationship between stress and impulsivity with regard to hazardous drinking. The specific importance of cumulative traumatic stress as a marker for problem drinking is also discussed.
BACKGROUND:Alcohol addiction may reflect adaptations to stress, reward, and regulatory brain systems. While extensive research has identified both stress and impulsivity as independent risk factors for drinking, few studies have assessed the interactive relationship between stress and impulsivity in terms of hazardous drinking within a community sample of regular drinkers. METHODS: One hundred and thirty regular drinkers (56M/74F) from the local community were assessed for hazardous and harmful patterns of alcohol consumption using the Alcohol Use Disorders Identification Test (AUDIT). All participants were also administered the Barratt Impulsiveness Scale (BIS-11) as a measure of trait impulsivity and the Cumulative Stress/Adversity Checklist (CSC) as a comprehensive measure of cumulative adverse life events. Standard multiple regression models were used to ascertain the independent and interactive nature of both overall stress and impulsivity as well as specific types of stress and impulsivity on hazardous and harmful drinking. RESULTS: Recent life stress, cumulative traumatic stress, overall impulsivity, and nonplanning-related impulsivity as well as cognitive and motor-related impulsivity were all independently predictive of AUDIT scores. However, the interaction between cumulative stress and total impulsivity scores accounted for a significant amount of the variance, indicating that a high to moderate number of adverse events and a high trait impulsivity rating interacted to affect greater AUDIT scores. The subscale of cumulative life trauma accounted for the most variance in AUDIT scores among the stress and impulsivity subscales. CONCLUSIONS: Findings highlight the interactive relationship between stress and impulsivity with regard to hazardous drinking. The specific importance of cumulative traumatic stress as a marker for problem drinking is also discussed.
Authors: Christina S Barr; Timothy K Newman; Stephen Lindell; Courtney Shannon; Maribeth Champoux; Klaus Peter Lesch; Stephen J Suomi; David Goldman; J Dee Higley Journal: Arch Gen Psychiatry Date: 2004-11
Authors: Gabriel Rubio; Mónica Jiménez; Roberto Rodríguez-Jiménez; Isabel Martínez; Martin Miguel Iribarren; Miguel Angel Jiménez-Arriero; Guillermo Ponce; Cesar Avila Journal: Alcohol Clin Exp Res Date: 2007-09-11 Impact factor: 3.455
Authors: Verica Milivojevic; Emily Ansell; Christine Simpson; Kristen M Siedlarz; Rajita Sinha; Helen C Fox Journal: Alcohol Clin Exp Res Date: 2017-02-01 Impact factor: 3.455
Authors: Adriaan Spruyt; Valentine Lemaigre; Bihiyga Salhi; Dinska Van Gucht; Helen Tibboel; Bram Van Bockstaele; Jan De Houwer; Jan Van Meerbeeck; Kristiaan Nackaerts Journal: Psychopharmacology (Berl) Date: 2015-03-13 Impact factor: 4.530