BACKGROUND AND PURPOSE:Lifetime risk (LTR) is an epidemiologic measure that expresses the probability of disease in the remaining lifetime for an index age. The LTR for stroke has not been reported for the Japanese population. METHODS: We included all participants from the Suita Study who were cardiovascular disease-free at baseline. Age (in years) was used as the time scale. Age-specific stroke incidence and all-cause mortality were calculated with the person-year method, and we estimated the sex- and index age-specific LTRs of first-ever stroke and its subtypes, taking into account the competing risk of death. RESULTS: We followed up 5498 participants from 1989 to 2005 for a total of 67 475 person-years. At age 55 years, the LTR for stroke, after accounting for competing risks of death, was 18.3% for men and 19.6% for women. The LTR for cerebral infarction was 14.6% for men and 15.5% for women, and the LTR for intracerebral hemorrhage was 2.4% for men and 1.4% for women at the index age of 55 years. The LTR for stroke remained similar across other index ages of 45, 55, and 65 years. CONCLUSIONS: The observed probabilities illustrate that approximately 1 in 5 men and women of middle age will experience stroke in their remaining lifetime. This easy understandable information can be used as an important index to assist in public health education and planning.
RCT Entities:
BACKGROUND AND PURPOSE: Lifetime risk (LTR) is an epidemiologic measure that expresses the probability of disease in the remaining lifetime for an index age. The LTR for stroke has not been reported for the Japanese population. METHODS: We included all participants from the Suita Study who were cardiovascular disease-free at baseline. Age (in years) was used as the time scale. Age-specific stroke incidence and all-cause mortality were calculated with the person-year method, and we estimated the sex- and index age-specific LTRs of first-ever stroke and its subtypes, taking into account the competing risk of death. RESULTS: We followed up 5498 participants from 1989 to 2005 for a total of 67 475 person-years. At age 55 years, the LTR for stroke, after accounting for competing risks of death, was 18.3% for men and 19.6% for women. The LTR for cerebral infarction was 14.6% for men and 15.5% for women, and the LTR for intracerebral hemorrhage was 2.4% for men and 1.4% for women at the index age of 55 years. The LTR for stroke remained similar across other index ages of 45, 55, and 65 years. CONCLUSIONS: The observed probabilities illustrate that approximately 1 in 5 men and women of middle age will experience stroke in their remaining lifetime. This easy understandable information can be used as an important index to assist in public health education and planning.
Authors: Tanvir Chowdhury Turin; Marcello Tonelli; Braden J Manns; Sofia B Ahmed; Pietro Ravani; Matthew James; Brenda R Hemmelgarn Journal: J Am Soc Nephrol Date: 2012-08-16 Impact factor: 10.121
Authors: Valery L Feigin; Grant Nguyen; Kelly Cercy; Catherine O Johnson; Tahiya Alam; Priyakumari G Parmar; Amanuel A Abajobir; Kalkidan H Abate; Foad Abd-Allah; Ayenew N Abejie; Gebre Y Abyu; Zanfina Ademi; Gina Agarwal; Muktar B Ahmed; Rufus O Akinyemi; Rajaa Al-Raddadi; Leopold N Aminde; Catherine Amlie-Lefond; Hossein Ansari; Hamid Asayesh; Solomon W Asgedom; Tesfay M Atey; Henok T Ayele; Maciej Banach; Amitava Banerjee; Aleksandra Barac; Suzanne L Barker-Collo; Till Bärnighausen; Lars Barregard; Sanjay Basu; Neeraj Bedi; Masoud Behzadifar; Yannick Béjot; Derrick A Bennett; Isabela M Bensenor; Derbew F Berhe; Dube J Boneya; Michael Brainin; Ismael R Campos-Nonato; Valeria Caso; Carlos A Castañeda-Orjuela; Jacquelin C Rivas; Ferrán Catalá-López; Hanne Christensen; Michael H Criqui; Albertino Damasceno; Lalit Dandona; Rakhi Dandona; Kairat Davletov; Barbora de Courten; Gabrielle deVeber; Klara Dokova; Dumessa Edessa; Matthias Endres; Emerito J A Faraon; Maryam S Farvid; Florian Fischer; Kyle Foreman; Mohammad H Forouzanfar; Seana L Gall; Tsegaye T Gebrehiwot; Johanna M Geleijnse; Richard F Gillum; Maurice Giroud; Alessandra C Goulart; Rahul Gupta; Rajeev Gupta; Vladimir Hachinski; Randah R Hamadeh; Graeme J Hankey; Habtamu A Hareri; Rasmus Havmoeller; Simon I Hay; Mohamed I Hegazy; Desalegn T Hibstu; Spencer L James; Panniyammakal Jeemon; Denny John; Jost B Jonas; Jacek Jóźwiak; Rizwan Kalani; Amit Kandel; Amir Kasaeian; Andre P Kengne; Yousef S Khader; Abdur R Khan; Young-Ho Khang; Jagdish Khubchandani; Daniel Kim; Yun J Kim; Mika Kivimaki; Yoshihiro Kokubo; Dhaval Kolte; Jacek A Kopec; Soewarta Kosen; Michael Kravchenko; Rita Krishnamurthi; G Anil Kumar; Alessandra Lafranconi; Pablo M Lavados; Yirga Legesse; Yongmei Li; Xiaofeng Liang; Warren D Lo; Stefan Lorkowski; Paulo A Lotufo; Clement T Loy; Mark T Mackay; Hassan Magdy Abd El Razek; Mahdi Mahdavi; Azeem Majeed; Reza Malekzadeh; Deborah C Malta; Abdullah A Mamun; Lorenzo G Mantovani; Sheila C O Martins; Kedar K Mate; Mohsen Mazidi; Suresh Mehata; Toni Meier; Yohannes A Melaku; Walter Mendoza; George A Mensah; Atte Meretoja; Haftay B Mezgebe; Tomasz Miazgowski; Ted R Miller; Norlinah M Ibrahim; Shafiu Mohammed; Ali H Mokdad; Mahmood Moosazadeh; Andrew E Moran; Kamarul I Musa; Ruxandra I Negoi; Minh Nguyen; Quyen L Nguyen; Trang H Nguyen; Tung T Tran; Thanh T Nguyen; Dina Nur Anggraini Ningrum; Bo Norrving; Jean J Noubiap; Martin J O’Donnell; Andrew T Olagunju; Oyere K Onuma; Mayowa O Owolabi; Mahboubeh Parsaeian; George C Patton; Michael Piradov; Martin A Pletcher; Farshad Pourmalek; V Prakash; Mostafa Qorbani; Mahfuzar Rahman; Muhammad A Rahman; Rajesh K Rai; Annemarei Ranta; David Rawaf; Salman Rawaf; Andre MN Renzaho; Stephen R Robinson; Ramesh Sahathevan; Amirhossein Sahebkar; Joshua A Salomon; Paola Santalucia; Itamar S Santos; Benn Sartorius; Aletta E Schutte; Sadaf G Sepanlou; Azadeh Shafieesabet; Masood A Shaikh; Morteza Shamsizadeh; Kevin N Sheth; Mekonnen Sisay; Min-Jeong Shin; Ivy Shiue; Diego A S Silva; Eugene Sobngwi; Michael Soljak; Reed J D Sorensen; Luciano A Sposato; Saverio Stranges; Rizwan A Suliankatchi; Rafael Tabarés-Seisdedos; David Tanne; Cuong Tat Nguyen; J S Thakur; Amanda G Thrift; David L Tirschwell; Roman Topor-Madry; Bach X Tran; Luong T Nguyen; Thomas Truelsen; Nikolaos Tsilimparis; Stefanos Tyrovolas; Kingsley N Ukwaja; Olalekan A Uthman; Yuri Varakin; Tommi Vasankari; Narayanaswamy Venketasubramanian; Vasiliy V Vlassov; Wenzhi Wang; Andrea Werdecker; Charles D A Wolfe; Gelin Xu; Yuichiro Yano; Naohiro Yonemoto; Chuanhua Yu; Zoubida Zaidi; Maysaa El Sayed Zaki; Maigeng Zhou; Boback Ziaeian; Ben Zipkin; Theo Vos; Mohsen Naghavi; Christopher J L Murray; Gregory A Roth Journal: N Engl J Med Date: 2018-12-20 Impact factor: 91.245