| Literature DB >> 20488703 |
Emmanuel O Carneiro1, Carolina H Andrade, Rodolpho C Braga, Andréa C B Tôrres, Rosângela O Alves, Luciano M Lião, Carlos A M Fraga, Eliezer J Barreiro, Valéria de Oliveira.
Abstract
A new bioactive compound of the N-acylhydrazone class, LASSBio-294, was shown to produce a cardioinotropic effect and vasodilation. In this study, we report the structure-based drug metabolism prediction, biosynthesis and identification of the major mammalian metabolite of LASSBio-294. Copyright 2010 Elsevier Ltd. All rights reserved.Entities:
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Year: 2010 PMID: 20488703 DOI: 10.1016/j.bmcl.2010.04.073
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN: 0960-894X Impact factor: 2.823