Literature DB >> 20488466

Repair of regurgitant bicuspid aortic valves: a systematic approach.

Munir Boodhwani1, Laurent de Kerchove, David Glineur, Jean Rubay, Jean-Louis Vanoverschelde, Philippe Noirhomme, Gebrine El Khoury.   

Abstract

OBJECTIVE: Patients with bicuspid aortic valves can present with aortic insufficiency caused by cusp disease or the aortic root pathology. We present our 13-year experience with a functional and systematic approach to bicuspid aortic valve repair.
METHODS: Between 1995 and 2008, 122 consecutive patients (mean age, 44 +/- 11 years) with bicuspid aortic valves underwent non-emergency valve repair for isolated aortic insufficiency (43%), aortic root dilatation (14%), or both (43%). Preoperative echocardiography identified aortic dilatation (n = 75), cusp prolapse (n = 96), and cusp restriction (n = 45) as mechanisms of aortic insufficiency. Raphé repair (n = 98) was performed by shaving (21%) or resection with primary closure (60%) or pericardial patch (18%). Functional aortic annuloplasty was performed using subcommissural annuloplasty (n = 51), ascending aortic replacement (n = 17), or aortic root replacement (n = 54) using a reimplantation (76%) or remodeling technique (24%).
RESULTS: There was no operative mortality. Five patients underwent early aortic valve reoperation (3 re-repairs). At discharge, 93% of patients had aortic insufficiency grade 0/1 and 7% of patients had grade 2. Seven additional patients underwent aortic valve reoperation during follow-up (2 re-repairs). Overall survival was 97% +/- 3% at 8 years. At 5 and 8 years follow-up, freedom from aortic valve reoperation was 94% +/- 2% and 83% +/- 5%, respectively, and freedom from aortic valve replacement was 96% +/- 2% and 90% +/- 5%, respectively. Freedom from recurrent aortic insufficiency (>2+) was 94% +/- 3% at 5 years. Freedom from thromboembolism and bleeding was 96% +/- 2% at 8 years.
CONCLUSION: A systematic approach to bicuspid aortic valve repair yields good early and midterm results. Repair of bicuspid valves for aortic insufficiency is a feasible and attractive alternative to mechanical valve replacement in young patients. Copyright 2010 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.

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Year:  2010        PMID: 20488466     DOI: 10.1016/j.jtcvs.2009.11.058

Source DB:  PubMed          Journal:  J Thorac Cardiovasc Surg        ISSN: 0022-5223            Impact factor:   5.209


  32 in total

1.  Aortic valve repair: a glimpse into the future.

Authors:  Munir Boodhwani; Gebrine El Khoury
Journal:  Eur J Cardiothorac Surg       Date:  2012-01       Impact factor: 4.191

2.  Modified patch repair for bicuspid aortic valve with thickened raphe.

Authors:  Takeshi Shimamoto; Tatsuhiko Komiya; Genichi Sakaguchi; Takeshi Maruo
Journal:  Gen Thorac Cardiovasc Surg       Date:  2012-05-19

3.  Complications after aortic valve repair and valve-sparing procedures.

Authors:  Michel Van Dyck; David Glineur; Laurent de Kerchove; Gébrine El Khoury
Journal:  Ann Cardiothorac Surg       Date:  2013-01

4.  Functional annulus remodelling using a prosthetic ring in tricuspid aortic valve repair: mid-term results.

Authors:  Khalil Fattouch; Sebastiano Castrovinci; Giacomo Murana; Giuseppe Nasso; Francesco Guccione; Pietro Dioguardi; Massimo Salardino; Giuseppe Bianco; Giuseppe Speziale
Journal:  Interact Cardiovasc Thorac Surg       Date:  2013-09-24

Review 5.  Is aortic valve repair or replacement with a bioprosthetic valve the best option for a patient with severe aortic regurgitation?

Authors:  Christos Tourmousoglou; Spiros Lalos; Dimitrios Dougenis
Journal:  Interact Cardiovasc Thorac Surg       Date:  2013-11-07

Review 6.  Current topics on bicuspid aortic valve: clinical aspects and surgical management.

Authors:  Hiroshi Furukawa; Kazuo Tanemoto
Journal:  Ann Thorac Cardiovasc Surg       Date:  2015-06-19       Impact factor: 1.520

Review 7.  Aortic valve repair update.

Authors:  Tatsuhiko Komiya
Journal:  Gen Thorac Cardiovasc Surg       Date:  2015-02-05

Review 8.  Why I choose to repair and not to replace the aortic valve?

Authors:  Athanasios Antoniou; Amer Harky; Mohamad Bashir; Gebrine El Khoury
Journal:  Gen Thorac Cardiovasc Surg       Date:  2018-04-05

9.  Individualized thoracic aortic replacement for the aortopathy of biscuspid aortic valve disease.

Authors:  Brian Lima; Judson B Williams; S Dave Bhattacharya; Asad A Shah; Nicholas Andersen; Andrew Wang; J Kevin Harrison; G Chad Hughes
Journal:  J Heart Valve Dis       Date:  2011-07

Review 10.  Aortic valve repair: indications and outcomes.

Authors:  Munir Boodhwani; Gebrine El Khoury
Journal:  Curr Cardiol Rep       Date:  2014       Impact factor: 2.931

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